Experimentally validated multiphase mathematical models of leg ulcers

  • Flegg, Jennifer, (Primary Chief Investigator (PCI))

Project: Research

Project Description

The Project aims to develop multiphase mathematical models that capture the complex spatiotemporal evolution
of cellular and chemical species during the formation and healing of a leg ulcer, biological processes which are
currently poorly understood. The intended outcome is to combine theory from fluid dynamics, mathematical
biology, numerical analysis and statistical inference to develop novel, validated partial differential equation models
whose numerical solution will provide needed insight into the underlying biological mechanisms. The potential
benefits of this mathematical framework include reducing the socioeconomic burden of leg ulcers in Australia,
which cost billions of dollars each year and cause a decreased quality of life.
StatusFinished
Effective start/end date15/08/161/05/17

Funding

  • Australian Research Council (ARC): AUD283,536.00
  • Australian Research Council (ARC): AUD71,945.00