Examining the role of INPP5E in human disease

Research output

Research output per year 2015 2015 2016 2017 2019 2020 2021 2024 2024

• 9 Article

Research output per year

Research output per year

Search results

• 2024

  Deletion of Aurora kinase A prevents the development of polycystic kidney disease in mice

  Tham, M. S., Cottle, D. L., Zylberberg, A. K., Short, K. M., Jones, L. K., Chan, P., Conduit, S. E., Dyson, J. M., Mitchell, C. A. & Smyth, I. M., 2024, In: Nature Communications. 15, 1, 18 p., 371.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access
  2 Citations (Scopus)
• 2021

  Superresolution Microscopy Reveals Distinct Phosphoinositide Subdomains Within the Cilia Transition Zone

  Conduit, S. E., Davies, E. M., Fulcher, A. J., Oorschot, V. & Mitchell, C. A., 30 Apr 2021, In: Frontiers in Cell and Developmental Biology. 9, 18 p., 634649.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access
  23 Citations (Scopus)
• 2020

  AKT signaling promotes DNA damage accumulation and proliferation in polycystic kidney disease

  Conduit, S. E., Davies, E. M., Ooms, L. M., Gurung, R., Mcgrath, M. J., Hakim, S., Cottle, D. L., Smyth, I. M., Dyson, J. M. & Mitchell, C. A., 1 Jan 2020, In: Human Molecular Genetics. 29, 1, p. 31-48 18 p.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  File
  18 Citations (Scopus)
• 2019

  β-catenin ablation exacerbates polycystic kidney disease progression

  Conduit, S. E., Hakim, S., Feeney, S. J., Ooms, L. M., Dyson, J. M., Abud, H. E. & Mitchell, C. A., 15 Jan 2019, In: Human Molecular Genetics. 28, 2, p. 230-244 15 p.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  File
  10 Citations (Scopus)
• 2017

  A compartmentalized phosphoinositide signaling axis at cilia is regulated by INPP5E to maintain cilia and promote Sonic Hedgehog medulloblastoma

  Conduit, SE., Ramaswamy, V., Remke, M., Watkins, DN., Wainwright, BJ., Taylor, MD., Mitchell, CA. & Dyson, JM., 26 Oct 2017, In: Oncogene. 36, 43, p. 5969-5984 16 p.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  File
  40 Citations (Scopus)

• INPP5E regulates phosphoinositide-dependent cilia transition zone function

  Dyson, J. M., Conduit, S. E., Feeney, S. J., Hakim, S., DiTommaso, T., Fulcher, A. J., Sriratana, A., Ramm, G., Horan, K. A., Gurung, R., Wicking, C., Smyth, I. & Mitchell, C. A., 2 Jan 2017, In: Journal of Cell Biology. 216, 1, p. 247-263 17 p.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  File
  92 Citations (Scopus)
• 2016

  Inpp5e suppresses polycystic kidney disease via inhibition of PI3K/Akt-dependent mTORC1 signaling

  Hakim, S., Dyson, J. M., Feeney, S. J., Davies, E. M., Sriratana, A., Koenig, M. N., Plotnikova, O., Smyth, I. M., Ricardo, S. D., Hobbs, R. M. & Mitchell, C. A., 2016, In: Human Molecular Genetics. 25, 11, p. 2295-2313 19 p.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  File
  42 Citations (Scopus)
• 2015

  INPP5E interacts with AURKA, linking phosphoinositide signaling to primary cilium stability

  Plotnikova, O., Seo, S., Cottle, D. L., Conduit, S. E., Hakim, S., Dyson, J. M., Mitchell, C. A. & Smyth, I. M., 2015, In: Journal of Cell Science. 128, 2, p. 364-372 9 p.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  File
  69 Citations (Scopus)

• Utilising the resources of the International Knockout Mouse Consortium: the Australian experience

  Cotton, L. M., Meilak, M., Templeton, T., Gonzalez, J., Nenci, A., Cooney, M. A., Truman, D., Rodda, F., Lynas, A., Viney, E. M., Rosenthal, N. A., Bianco, D. M., O'Bryan, M. K. & Smyth, I. M., 2015, In: Mammalian Genome. 26, 3-4, p. 142 - 158 17 p.

  Research output: Contribution to journal › Article › Research › peer-review
  13 Citations (Scopus)