Evaluating direct and indirect effects of SARS-CoV-2 on multiple organ systems using stem cell-derived human tissues

  • Little, Melissa (Primary Chief Investigator (PCI))
  • Subbarao , Kanta (Chief Investigator (CI))
  • Asselin-Labat, Marie-Liesse (Chief Investigator (CI))
  • Porello, Enzo (Chief Investigator (CI))
  • Elliott, David (Chief Investigator (CI))
  • Hidalgo, Alejandro (Chief Investigator (CI))
  • Polo, Jose (Chief Investigator (CI))
  • Ramialison, Mirana (Chief Investigator (CI))
  • Lockhart, Paul J (Chief Investigator (CI))
  • Lewin, Sharon (Chief Investigator (CI))
  • Mackenzie, Jason (Chief Investigator (CI))
  • Leventer, Richard Jacob (Chief Investigator (CI))
  • Mackay, Mark T (Chief Investigator (CI))
  • Stanley, Edouard (Chief Investigator (CI))
  • Elefanty, Andrew, Murdoch Children's Research Institute (Chief Investigator (CI))
  • Ng, Elizabeth S. (Chief Investigator (CI))
  • Bozaoglu, Kiymet (Chief Investigator (CI))
  • Conyers, Rachel K. (Chief Investigator (CI))
  • Forbes, Thomas A. (Chief Investigator (CI))
  • Howden, Sarah (Chief Investigator (CI))
  • Vanslambrouck, Jessica (Chief Investigator (CI))
  • Pellegrini, Marc (Chief Investigator (CI))

Project: Research

Project Details

Project Description

There is growing evidence that SARS-CoV-2 can damage organs beyond lung, including heart, blood vessels, immune cells, kidney and even neural tissue. Limited understanding of the impact of SARS-CoV-2 on such tissues limits our capacity to treat patients optimally and anticipate long term complications. This collaborative program will generate a wide variety of stem cell-derived human tissues to study viral infection and impact on comorbidities. This will increase our understanding of disease pathology, change clinical care and facilitate the development of targeted treatment options.
Effective start/end date16/09/2015/09/21