Early Goal-Directed Sedation compared with standard care in mechanically ventilated critically ill patients: a prospective multicentre randomised controlled trial.

Shehabi, Yahya (Primary Chief Investigator (PCI))
Bailey, Michael (Chief Investigator (CI))
Bellomo, Rinaldo (Chief Investigator (CI))
Howe, Belinda (Chief Investigator (CI))
McArthur, Colin (Chief Investigator (CI))
Reade, Michael C. (Chief Investigator (CI))
Seppelt, Ian M (Chief Investigator (CI))

Project: Research

Status	Finished
Effective start/end date	1/01/13 → 31/12/18

Funding

National Health and Medical Research Council (NHMRC) (Australia): AUD2,752,725.00

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2 Article
1 Review Article

Early sedation with dexmedetomidine in critically ill patients
Shehabi, Y., Howe, B. D., Bellomo, R., Arabi, Y. M., Bailey, M., Bass, F. E., Bin Kadiman, S., McArthur, C. J., Murray, L., Reade, M. C., Seppelt, I. M., Takala, J., Wise, M. P. & Webb, S. A., 27 Jun 2019, In: The New England Journal of Medicine. 380, 26, p. 2506-2517 12 p.
Research output: Contribution to journal › Article › Research › peer-review

139 Citations (Scopus)
The intensive care delirium research agenda: a multinational, interprofessional perspective
Pandharipande, P. P., Ely, E. W., Arora, R. C., Balas, M. C., Boustani, M. A., La Calle, G. H., Cunningham, C., Devlin, J. W., Elefante, J., Han, J-H., MacLullich, A. M., Maldonado, J. R., Morandi, A., Needham, D. M., Page, V. J., Rose, L., Salluh, J. I. F., Sharshar, T., Shehabi, Y., Skrobik, Y. & 2 others, Slooter, A. J. C. & Smith, H. A. B., 1 Sep 2017, In: Intensive Care Medicine. 43, 9, p. 1329-1339 11 p.
Research output: Contribution to journal › Review Article › Research › peer-review

89 Citations (Scopus)
The SPICE III study protocol and analysis plan: a randomised trial of early goal-directed sedation compared with standard care in mechanically ventilated patients (Protocol)
Shehabi, Y., Forbes, A. B., Arabi, Y., Bass, F., Bellomo, R., Kadiman, S., Howe, B. D., McArthur, C., Reade, M. C., Seppelt, I., Takala, J., Webb, S., Wise, M. P. & for the SPICE III study investigators, the Australian and New Zealand Intensive Care Society Clinical Trials Group and the Australian and New Zealand Intensive Care Research Centre, 1 Dec 2017, In: Critical Care and Resuscitation. 19, 4, p. 318-326 9 p.
Research output: Contribution to journal › Article › Other › peer-review

9 Citations (Scopus)

Early Goal-Directed Sedation compared with standard care in mechanically ventilated critically ill patients: a prospective multicentre randomised controlled trial.

Project Details

Funding

Research output

Early sedation with dexmedetomidine in critically ill patients

The intensive care delirium research agenda: a multinational, interprofessional perspective

The SPICE III study protocol and analysis plan: a randomised trial of early goal-directed sedation compared with standard care in mechanically ventilated patients (Protocol)