Dual Targeting of the Androgen Receptor for Effective and Durable Control of Lethal Prostate Cancer

  • Tilley, Wayne D. (Primary Chief Investigator (PCI))
  • Risbridger, Gail (Chief Investigator (CI))
  • Raj, Ganesh V (Chief Investigator (CI))
  • Selth, Luke A. (Chief Investigator (CI))
  • Taylor, Renea (Chief Investigator (CI))
  • Joshua, Anthony M (Chief Investigator (CI))

Project: Research

Project Details

Project Description

Preventing binding of androgens to the androgen receptor is the mainstay treatment for advanced prostate cancer, but resistance inevitably develops and the disease becomes lethal. We will develop a new drug that targets a part of the androgen receptor unrelated to its androgen binding function to overcome resistance to current therapy. As this drug will be effective in all stages of prostate cancer, it has high potential to improve survival outcomes for men with prostate cancer.
Effective start/end date1/01/1731/12/20


  • National Health and Medical Research Council (NHMRC) (Australia): A$1,095,560.00