Drug targeting to sites of lymph-adipose interaction to transform the treatment of disease

Project: Research

Status	Finished
Effective start/end date	1/01/16 → 31/12/18

Association of a vaccine adjuvant with endogenous HDL increases lymph uptake and dendritic cell activation
Gracia, G., Cao, E., Kochappan, R., Porter, C. J. H., Johnston, A. P. R. & Trevaskis, N. L., Mar 2022, In: European Journal of Pharmaceutics and Biopharmaceutics. 172, p. 240-252 13 p.
Research output: Contribution to journal › Article › Research › peer-review

Open Access

6 Citations (Scopus)
Obesity-associated mesenteric lymph leakage impairs the trafficking of lipids, lipophilic drugs and antigens from the intestine to mesenteric lymph nodes
Mikrani, R., Styles, I. K., Hoang, T. A., Abdallah, M., Senyschyn, D., Porter, C. J. H., Cao, E. & Trevaskis, N. L., Nov 2022, In: European Journal of Pharmaceutics and Biopharmaceutics. 180, p. 319-331 13 p.
Research output: Contribution to journal › Article › Research › peer-review

4 Citations (Scopus)
Mesenteric lymphatic dysfunction promotes insulin resistance and represents a potential treatment target in obesity
Cao, E., Watt, M. J., Nowell, C. J., Quach, T., Simpson, J. S., De Melo Ferreira, V., Agarwal, S., Chu, H., Srivastava, A., Anderson, D., Gracia, G., Lam, A., Segal, G., Hong, J., Hu, L., Phang, K. L., Escott, A. B. J., Windsor, J. A., Phillips, A. R. J. & Creek, D. J. & 3 others, Harvey, N. L., Porter, C. J. H. & Trevaskis, N. L., 20 Sept 2021, In: Nature Metabolism. 3, 9, p. 1175-1188 14 p.
Research output: Contribution to journal › Article › Research › peer-review

81 Citations (Scopus)

Project Details