There is an unmet need for the capacity to generate small molecules that modulate therapeutically and
biologically important protein targets.
Fragment-based drug design (FBDD) provides a rational approach to generate such biologically active
The Distributed FBDD Facility will provide a mechanism for researchers throughout Australia to access the
necessary infrastructure to undertake FBDD projects against a range of biologically important targets. The facility
will enable access to high-throughput NMR spectroscopy and surface plasmon resonance, it will generate the
capacity for automation in chemical synthesis and sample preparation to expedite the development of novel