Dissecting the functions of accessory subunits in mitochondrial complex I

AIFM1 is a component of the mitochondrial disulfide relay that drives complex I assembly through efficient import of NDUFS5

Salscheider, S. L., Gerlich, S., Cabrera-Orefice, A., Peker, E., Rothemann, R. A., Murschall, L. M., Finger, Y., Szczepanowska, K., Ahmadi, Z. A., Guerrero-Castillo, S., Erdogan, A., Becker, M., Ali, M., Habich, M., Petrungaro, C., Burdina, N., Schwarz, G., Klußmann, M., Neundorf, I., Stroud, D. A., & 4 othersRyan, M. T., Trifunovic, A., Brandt, U. & Riemer, J., 1 Sept 2022, In: The EMBO Journal. 41, 17, 21 p., e110784.

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Most mitochondrial dGTP is tightly bound to respiratory complex I through the NDUFA10 subunit

Molina-Granada, D., González-Vioque, E., Dibley, M. G., Cabrera-Pérez, R., Vallbona-Garcia, A., Torres-Torronteras, J., Sazanov, L. A., Ryan, M. T., Cámara, Y. & Martí, R., 2022, In: Communications Biology. 5, 1, 16 p., 620.

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Optic atrophy–associated TMEM126A is an assembly factor for the ND4-module of mitochondrial complex I

Formosa, L. E., Reljic, B., Sharpe, A. J., Hock, D. H., Muellner-Wong, L., Stroud, D. A. & Ryan, M. T., 27 Apr 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 17, 9 p., e2019665118.

Research output: Contribution to journal › Article › Research › peer-review