Developing new therapies to improve Small Cell Lung Cancer patient outcomes

Gough, Daniel (Primary Chief Investigator (PCI))

Hudson Institute - Centre for Cancer Research

Project: Research

Status	Finished
Effective start/end date	1/04/20 → 31/03/24

5 Article

A STAT3 protein complex required for mitochondrial mRNA stability and cancer
Fernando, C. D., Jayasekara, W. S. N., Inampudi, C., Kohonen-Corish, M. R. J., Cooper, W. A., Beilharz, T. H., Josephs, T. M., Garama, D. J. & Gough, D. J., 26 Sept 2023, In: Cell Reports. 42, 9, 14 p., 113033.
Research output: Contribution to journal › Article › Research › peer-review

Open Access

9 Citations (Scopus)
Ligand-dependent hedgehog signaling maintains an undifferentiated, malignant osteosarcoma phenotype
Vaghjiani, V. G., Cochrane, C. R., Jayasekara, W. S. N., Chong, W. C., Szczepny, A., Kumar, B., Martelotto, L. G., McCaw, A., Carey, K., Kansara, M., Thomas, D. M., Walkley, C., Mudge, S., Gough, D. J., Downie, P. A., Peacock, C. D., Matsui, W., Watkins, D. N. & Cain, J. E., 17 Nov 2023, In: Oncogene. 42, 47, p. 3529–3541 13 p.
Research output: Contribution to journal › Article › Research › peer-review

Open Access

1 Citation (Scopus)
MYC drives platinum resistant SCLC that is overcome by the dual PI3K-HDAC inhibitor fimepinostat
Chen, J., Guanizo, A. C., Jakasekara, W. S. N., Inampudi, C., Luong, Q., Garama, D. J., Alamgeer, M., Thakur, N., DeVeer, M., Ganju, V., Watkins, D. N., Cain, J. E. & Gough, D. J., Dec 2023, In: Journal of Experimental and Clinical Cancer Research. 42, 1, 14 p., 100.
Research output: Contribution to journal › Article › Research › peer-review

Open Access

18 Citations (Scopus)

Animal Research Platform (MARP)
Findlay, C. (Manager)
Faculty of Medicine Nursing and Health Sciences Research Platforms
Facility/equipment: Facility
Biomedical Imaging (MBI)
Reid, K. (Manager), Brkljaca, R. (Manager), Hagemeyer, C. (Other) & Wright, D. (Other)
Office of the Vice-Provost (Research and Research Infrastructure)
Facility/equipment: Facility
FlowCore
Fryga, A. (Manager)
Faculty of Medicine Nursing and Health Sciences Research Platforms
Facility/equipment: Facility