Determining the impacts of epigenetic modifying drugs on germline programming and offspring health

  • Western, Patrick (Primary Chief Investigator (PCI))
  • Gardner, David (Chief Investigator (CI))
  • Adelson, David Louis (Chief Investigator (CI))
  • Hill, Rachel (Chief Investigator (CI))
  • Ziegler, David (Chief Investigator (CI))

Project: Research

Project Description

New drugs have been developed that block specific enzymes that regulate epigenetic pathways in cells. These pathways significantly affect growth and development in offspring and may represent a risk to future children of patients taking the drug. This project will determine these risks and provide data for developing clinical guidelines for safe use of the drugs.
Effective start/end date1/01/1831/12/20