Determining the impacts of epigenetic modifying drugs on germline programming and offspring health

  • Western, Patrick (Primary Chief Investigator (PCI))
  • Gardner, David (Chief Investigator (CI))
  • Adelson, David Louis (Chief Investigator (CI))
  • Hill, Rachel (Chief Investigator (CI))
  • Ziegler, David (Chief Investigator (CI))

Project: Research

Project Details

Project Description

New drugs have been developed that block specific enzymes that regulate epigenetic pathways in cells. These pathways significantly affect growth and development in offspring and may represent a risk to future children of patients taking the drug. This project will determine these risks and provide data for developing clinical guidelines for safe use of the drugs.
Effective start/end date1/01/1831/12/21