Defining the structural basis of lipid mediated T cell immunity

Project: Research

Status	Finished
Effective start/end date	1/01/21 → 31/12/24

CD1 displays its own negative regulators
Shahine, A., Van Rhijn, I., Rossjohn, J. & Moody, D. B., Aug 2023, In: Current Opinion in Immunology. 83, 7 p., 102339.
Research output: Contribution to journal › Review Article › Research › peer-review

8 Link opens in a new tab Citations (Scopus)
CD1 lipidomes reveal lipid-binding motifs and size-based antigen-display mechanisms
Huang, S., Shahine, A., Cheng, T.-Y., Chen, Y.-L., Ng, S. W., Balaji, G. R., Farquhar, R., Gras, S., Hardman, C. S., Altman, J. D., Tahiri, N., Minnaard, A. J., Ogg, G. S., Mayfield, J. A., Rossjohn, J. & Moody, D. B., 12 Oct 2023, In: Cell. 186, 21, p. 4583-4596.e13 13 p.
Research output: Contribution to journal › Article › Research › peer-review

Open Access

31 Link opens in a new tab Citations (Scopus)
Enhanced CD1d phosphatidylserine presentation using a single-domain antibody promotes immunomodulatory CD1d-TIM-3 interactions
Lameris, R., Shahine, A., Veth, M., Westerman, B., Godfrey, D. I., Lutje Hulsik, D., Brouwer, P., Rossjohn, J., de Gruijl, T. D. & van der Vliet, H. J., 1 Dec 2023, In: Journal for ImmunoTherapy of Cancer. 11, 12, 10 p., e007631.
Research output: Contribution to journal › Article › Research › peer-review

Open Access

4 Link opens in a new tab Citations (Scopus)

2025 Chemistry Biology Interface Horizon Prize
Shahine, A. (Recipient), 2025
Prize: Prize (including medals and awards)
Director's Highly Commended Publication Award
Shahine, A. (Recipient), 2023
Prize: Prize (including medals and awards)

Project Details