Defining the machinery for mitochondrial turnover governed by the Parkinson's Disease proteins PINK1 and Parkin

Lazarou, Michael (Primary Chief Investigator (PCI))
Ryan, Mike (Chief Investigator (CI))

Biochemistry & Molecular Biology

Project: Research

Status	Finished
Effective start/end date	1/01/16 → 31/12/18

Funding

NHMRC - National Health and Medical Research Council (Australia): A$432,987.00

Control of mitophagy initiation and progression by the TBK1 adaptors NAP1 and SINTBAD
Adriaenssens, E., Nguyen, T. N., Sawa-Makarska, J., Khuu, G., Schuschnig, M., Shoebridge, S., Skulsuppaisarn, M., Watts, E. M., Csalyi, K. D., Padman, B. S., Lazarou, M. & Martens, S., Nov 2024, In: Nature Structural and Molecular Biology. 31, 11, p. 1717–1731 15 p.
Research output: Contribution to journal › Article › Research › peer-review

Open Access

21 Link opens in a new tab Citations (Scopus)
Exposure of the inner mitochondrial membrane triggers apoptotic mitophagy
Saunders, T. L., Windley, S. P., Gervinskas, G., Balka, K. R., Rowe, C., Lane, R., Tailler, M., Nguyen, T. N., Ramm, G., Lazarou, M., De Nardo, D., Kile, B. T. & McArthur, K., Mar 2024, In: Cell Death and Differentiation. 31, 3, p. 335-347 13 p.
Research output: Contribution to journal › Article › Research › peer-review

Open Access

39 Link opens in a new tab Citations (Scopus)
Interaction of PINK1 with nucleotides and kinetin
Gan, Z. Y., Callegari, S., Nguyen, T. N., Kirk, N. S., Leis, A., Lazarou, M., Dewson, G. & Komander, D., 19 Jan 2024, In: Science Advances. 10, 3, 12 p., eadj7408.
Research output: Contribution to journal › Article › Research › peer-review

Open Access

10 Link opens in a new tab Citations (Scopus)