Defining the epigenetic origins of maternally inherited disease.

  • Western, Patrick (Primary Chief Investigator (PCI))
  • Gardner, David (Chief Investigator (CI))
  • Voss, Anne K (Associate Investigator (AI))
  • van den Buuse, Maarten (Chief Investigator (CI))
  • Adelson, David Louis (Chief Investigator (CI))
  • Sims, Natalie A. (Associate Investigator (AI))
  • Hutt, Karla (Associate Investigator (AI))
  • Dickinson, Hayley (Chief Investigator (CI))
  • Stringer, Jessica (Associate Investigator (AI))
  • Hill, Rachel (Associate Investigator (AI))
  • Gibson, William (Associate Investigator (AI))

Project: Research

Project Details

Project Description

Epigenetic (non genetic) changes to the DNA in sperm and eggs can alter outcomes in children. Despite the potential for drugs and diet to mediate some of these inherited effects, the processes involved are very poorly understood. By determining the mechanisms that regulate epigenetic inheritance, this project will improve our understanding of how epigenetic mechanisms acting in the parent, can mediate inherited disease and life-long health outcomes in our children.
Effective start/end date1/01/1831/12/20