Defining the efficacy of blocking Serine phosphorylated STAT3 in the treatment of gastric cancer

Gough, Daniel (Primary Chief Investigator (PCI))

Hudson Institute - Centre for Cancer Research

Project: Research

Status	Finished
Effective start/end date	30/09/16 → 29/09/18

Funding

United States Department of Defense (DOD): A$516,743.00

Keywords

Gastric cancer
STAT3
Mitochondria
Mouse models

2 Article

STAT3 serine phosphorylation is required for TLR4 metabolic reprogramming and IL-1β expression
Balic, J. J., Albargy, H., Luu, K., Kirby, F. J., Jayasekara, W. S. N., Mansell, F., Garama, D. J., De Nardo, D., Baschuk, N., Louis, C., Humphries, F., Fitzgerald, K., Latz, E., Gough, D. J. & Mansell, A., 30 Jul 2020, In: Nature Communications. 11, 1, 11 p., 3816.
Research output: Contribution to journal › Article › Research › peer-review

Open Access
File

33 Citations (Scopus)
Cyclin-dependent kinase 7 is a therapeutic target in high-grade glioma
Greenall, S. A., Lim, Y. C., Mitchell, C. B., Ensbey, K. S., Stringer, B. W., Wilding, A. L., O'Neill, G. M., McDonald, K. L., Gough, D. J., Day, B. W. & Johns, T. G., 1 Jan 2017, In: Oncogenesis. 6, 5, 13 p., e336.
Research output: Contribution to journal › Article › Research › peer-review

Open Access
File

45 Citations (Scopus)

Animal Research Platform (MARP)
Tanya Lennane (Manager)
Faculty of Medicine Nursing and Health Sciences Research Platforms
Facility/equipment: Facility
FlowCore
Andrew Fryga (Manager)
Faculty of Medicine Nursing and Health Sciences Research Platforms
Facility/equipment: Facility
MHTP Medical Genomics Facility
Trevor Wilson (Manager)
Hudson Institute - Department of Molecular and Translational Science
Facility/equipment: Facility