Defining the central role of podocyte depletion in the development, progression and management of glomerular disease

Bertram, John (Primary Chief Investigator (PCI))
Nikolic-Paterson, David (Chief Investigator (CI))
Denton, Katherine (Chief Investigator (CI))

Project: Research

Status	Finished
Effective start/end date	1/01/17 → 31/12/19

Funding

National Health and Medical Research Council (NHMRC) (Australia): A$690,854.00

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3 Article
1 Review Article

MTOR-mediated podocyte hypertrophy regulates glomerular integrity in mice and humans
Puelles, V. G., van der Wolde, J. W., Wanner, N., Scheppach, M. W., Cullen-McEwen, L. A., Bork, T., Lindenmeyer, M. T., Gernhold, L., Wong, M. N., Braun, F., Cohen, C. D., Kett, M. M., Kuppe, C., Kramann, R., Saritas, T., Van Roeyen, C. R., Moeller, M. J., Tribolet, L., Rebello, R., Sun, Y. B. Y. & 13 others, Li, J., Müller-Newen, G., Hughson, M. D., Hoy, W. E., Person, F., Wiech, T., Ricardo, S. D., Kerr, P. G., Denton, K. M., Furic, L., Huber, T. B., Nikolic-Paterson, D. J. & Bertram, J. F., 19 Sep 2019, In: JCI Insight. 4, 18, 18 p., e99271.
Research output: Contribution to journal › Article › Research › peer-review

Open Access
File

28 Citations (Scopus)
Novel 3D analysis using optical tissue clearing documents the evolution of murine rapidly progressive glomerulonephritis
Puelles, V. G., Fleck, D., Ortz, L., Papadouri, S., Strieder, T., Böhner, A. M. C., van der Wolde, J. W., Vogt, M., Saritas, T., Kuppe, C., Fuss, A., Menzel, S., Klinkhammer, B. M., Müller-Newen, G., Heymann, F., Decker, L., Braun, F., Kretz, O., Huber, T. B., Susaki, E. A. & 9 others, Ueda, H. R., Boor, P., Floege, J., Kramann, R., Kurts, C., Bertram, J. F., Spehr, M., Nikolic-Paterson, D. J. & Moeller, M. J., Aug 2019, In: Kidney International. 96, 2, p. 505–516 12 p.
Research output: Contribution to journal › Article › Research › peer-review

Open Access
File

29 Citations (Scopus)
Quantifying podocyte depletion: theoretical and practical considerations
Puelles, V. G., Bertram, J. F. & Moeller, M. J., 1 Jul 2017, In: Cell and Tissue Research. 369, 1, p. 229-236 8 p.
Research output: Contribution to journal › Review Article › Other › peer-review

13 Citations (Scopus)

Animal Research Platform (MARP)
Tanya Lennane (Manager)
Faculty of Medicine Nursing and Health Sciences Research Platforms
Facility/equipment: Facility
Bioinformatics Platform
David Powell (Manager)
Faculty of Medicine Nursing and Health Sciences Research Platforms
Facility/equipment: Facility
Histology Platform
Camilla Cohen (Manager)
Faculty of Medicine Nursing and Health Sciences Research Platforms
Facility/equipment: Facility

Defining the central role of podocyte depletion in the development, progression and management of glomerular disease

Project Details

Funding

Research output

MTOR-mediated podocyte hypertrophy regulates glomerular integrity in mice and humans

Novel 3D analysis using optical tissue clearing documents the evolution of murine rapidly progressive glomerulonephritis

Quantifying podocyte depletion: theoretical and practical considerations

Equipment

Animal Research Platform (MARP)

Bioinformatics Platform

Histology Platform