Project Details
Project Description
This project aims to undertake discovery research to characterise the transcriptional programs that underpin the development of unconventional immune cells. This project expects to generate new knowledge in the area of developmental immunology by using cutting-edge molecular and cellular techniques to examine the seeding of immune cells in development. It is expected that this project will advance our understanding of immune cell biology and the programs that control them. Significantly strengthening national excellence in unconventional immune cell research and providing innovative methodology. This should provide significant benefits, such as a comprehensive open-access transcriptional map of developing unconventional immune cells.
| Status | Finished |
|---|---|
| Effective start/end date | 13/01/20 → 31/07/22 |
Funding
- ARC - Australian Research Council: A$118,902.00
Research output
- 5 Article
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Identifying immune signatures of sepsis to increase diagnostic accuracy in very preterm babies
Das, A., Ariyakumar, G., Gupta, N., Kamdar, S., Barugahare, A., Deveson-Lucas, D., Gee, S., Costeloe, K., Davey, M. S., Fleming, P. & Gibbons, D. L., 9 Jan 2024, In: Nature Communications. 15, 1, 15 p., 388.Research output: Contribution to journal › Article › Research › peer-review
Open Access24 Link opens in a new tab Citations (Scopus) -
Circulating effector γδ T cell populations are associated with acute coronavirus disease 19 in unvaccinated individuals
von Borstel, A., Nguyen, T. H. O., Rowntree, L. C., Ashhurst, T. M., Allen, L. F., Howson, L. J., Holmes, N. E., Smibert, O. C., Trubiano, J. A., Gordon, C. L., Cheng, A. C., Kent, S. J., Rossjohn, J., Kedzierska, K. & Davey, M. S., Apr 2023, In: Immunology and Cell Biology. 101, 4, p. 321-332 12 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access10 Link opens in a new tab Citations (Scopus) -
Repeated Plasmodium falciparum infection in humans drives the clonal expansion of an adaptive γδ T cell repertoire
von Borstel, A., Chevour, P., Arsovski, D., Krol, J. M. M., Howson, L. J., Berry, A. A., Day, C. L., Ogongo, P., Ernst, J. D., Nomicos, E. Y. H., Boddey, J. A., Giles, E. M., Rossjohn, J., Traore, B., Lyke, K. E., Williamson, K. C., Crompton, P. D. & Davey, M. S., 1 Dec 2021, In: Science Translational Medicine. 13, 622, 15 p., abe7430.Research output: Contribution to journal › Article › Research › peer-review
41 Link opens in a new tab Citations (Scopus)
Equipment
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FlowCore (FLOW)
Fryga, A. (Manager)
Faculty of Medicine Nursing and Health Sciences Research PlatformsFacility/equipment: Facility
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High-performance Computing (M3/MASSIVE)
Powell, D. (Manager) & Tan, G. (Manager)
Office of the Vice-Provost (Research and Research Infrastructure)Facility/equipment: Facility
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MHTP Medical Genomics Facility
Wilson, T. (Manager)
Hudson Institute - Department of Molecular and Translational ScienceFacility/equipment: Facility