Defining a role for non-coding RNAs in gonadal sex differentiation.

Project: Research

Project Description

This project aims to enhance knowledge in the area of developmental biology, studying how gene regulation by
so-called non-coding RNAs contributes to tissue patterning. A unique model system will be used for which we
have an international reputation: gonadal development in the chicken embryo. Novel molecular approaches that
exploit the chicken model will be used to study the role of microRNAs and a long non-coding RNA in patterning
the embryonic gonad. The project will provide a deeper understanding of how genes operate to control tissue
patterning and organogenesis. It will inform the field of sex determination specifically, and, more broadly, stem cell
biology and tissue engineering.
StatusFinished
Effective start/end date1/01/1631/12/18

Funding

  • Australian Research Council (ARC): AUD327,800.00
  • Monash University