Controlling cell polarity and asymmetric cell division in space and time

Asymmetric cell division is a specialised form of cell division essential for the development of all organisms. The
two meiotic divisions of the oocyte are extreme examples of asymmetric cell division that allow a reduction in
chromosome content while retaining cytoplasmic vestments necessary for development. Successful asymmetric
cell division requires the integration of cell cycle events with cell polarity and understanding how this is achieved
will improve our understanding of how to generate a healthy embryo in women, endangered species and in
animals of commercial importance. Further, we will make fundamental discoveries that will impact on our
understanding of mechanisms of cell division in all organisms.