Confocal and single molecule microscopes for Systems Microscopy

This projects aims to establish Australia’s first System Microscopy facility and request funding for dedicated live- cell confocal and single molecule fluorescence microscopes. In Systems Microscopy, the imaging workflow is automated so that large and unbiased data sets of the spatiotemporal organisation of molecules and cells can be generated. Combined with statistical and bioinformatics analyses, image-derived data provides system-wide information that is not easily obtainable with other -omics approaches, from inference of regulatory networks to machine learning-based detection of cellular subpopulations and behaviours. Staff and IT infrastructure for the new facility is funded by UNSW as an in-kind contribution.