Project Description
Our aim is to design multi-functional nanoparticles that can be tracked by multiple bio-imaging techniques, such
as magnetic resonance imaging (MRI) and positron emission tomography (PET) imaging. The nanoparticles we
design will be targetable to specific cell populations and capable of delivering drugs. These 'theranostic'
nanoparticles will be able to attenuate their imaging signal on release of their drug payload. This work is
significant as it will enable a new approach to extremely accurate and sensitive imaging of tumours combined with targeted therapy, with the expected significant benefits of imaging much smaller tumours than currently possible
(sensitivity) combined with a simultaneous early therapeutic intervention.
as magnetic resonance imaging (MRI) and positron emission tomography (PET) imaging. The nanoparticles we
design will be targetable to specific cell populations and capable of delivering drugs. These 'theranostic'
nanoparticles will be able to attenuate their imaging signal on release of their drug payload. This work is
significant as it will enable a new approach to extremely accurate and sensitive imaging of tumours combined with targeted therapy, with the expected significant benefits of imaging much smaller tumours than currently possible
(sensitivity) combined with a simultaneous early therapeutic intervention.
| Status | Active |
|---|---|
| Effective start/end date | 1/01/16 → 31/12/19 |
Funding
- Australian Research Council (ARC): AUD441,295.00
- Australian Research Council (ARC)
- Monash University
- University of South Australia