Combating adaptive resistance to tageted therapy in triple-negative breast cancer

Nguyen, Lan (Primary Chief Investigator (PCI))
Swarbrick, Alexander (Associate Investigator (AI))
Richardson, Gary (Associate Investigator (AI))
Loi, Sherene (Associate Investigator (AI))
Daly, Roger (Associate Investigator (AI))

Project: Research

Status	Finished
Effective start/end date	15/02/19 → 14/02/23

6 Article
2 Review Article

Akt phosphorylates insulin receptor substrate to limit PI3K-mediated PIP3 synthesis
Kearney, A. L., Norris, D. M., Ghomlaghi, M., Wong, M. K. L., Humphrey, S. J., Carroll, L., Yang, G., Cooke, K. C., Yang, P., Geddes, T. A., Shin, S., Fazakerley, D. J., Nguyen, L. K., James, D. E. & Burchfield, J. G., Jul 2021, In: eLife. 10, 32 p., e66942.
Research output: Contribution to journal › Article › Research › peer-review

Open Access

10 Citations (Scopus)
Dynamic modelling of the PI3K/MTOR signalling network uncovers biphasic dependence of mTORC1 activity on the mTORC2 subunit SIN1
Ghomlaghi, M., Yang, G., Shin, S-Y., James, D. E. & Nguyen, L. K., Sep 2021, In: PLoS Computational Biology. 17, 9, 26 p., e1008513.
Research output: Contribution to journal › Article › Research › peer-review

Open Access

3 Citations (Scopus)
Feedback, crosstalk and competition: Ingredients for emergent non‐linear behaviour in the pi3k/mtor signalling network
Ghomlaghi, M., Hart, A., Hoang, N., Shin, S. & Nguyen, L. K., 1 Jul 2021, In: International Journal of Molecular Sciences. 22, 13, 14 p., 6944.
Research output: Contribution to journal › Review Article › Research › peer-review

Open Access

8 Citations (Scopus)

Animal Research Platform (MARP)
Christine Findlay (Manager)
Faculty of Medicine Nursing and Health Sciences Research Platforms
Facility/equipment: Facility
MASSIVE
Slava Kitaeff (Manager) & David Powell (Manager)
Office of the Vice-Provost (Research and Research Infrastructure)
Facility/equipment: Facility
Monash Proteomics & Metabolomics Facility
Ralf Schittenhelm (Manager)
Faculty of Medicine Nursing and Health Sciences Research Platforms
Facility/equipment: Facility