Characterising the effects of polyphenols on oxidative stress and inflammation in MPO-ANCA vasculitis.

  • Houghton, Michael (Primary Chief Investigator (PCI))
  • Huang, U-Shane (Chief Investigator (CI))

Project: Research

Project Details

Project Description

This project proposes the use of a polyphenol-rich extract to reduce leukocytic ROS generation and inflammation, and subsequent neutrophil extracellular trap (NET) formation, to attenuate damage to the kidney vasculature in a murine model of autoimmune MPO-AAV.
Effective start/end date1/03/2329/02/24