The objective is to establish a joint facility between Monash University and the University of Sydney to determine flow and particle size characteristics of micronised and nano-sized particles in simulated lung airways. The proposed facilities consists of a 3D Tomographic Imaging System, with its unprecedented resolution and dynamic measurement capabilities, and state of the art particle sizing and will provide advanced research capabilities including three dimensional imaging, measurement of flow, and sizing of particles under different breathing patterns in an in-vitro respiratory tract airway environment for drug delivery, clinical and anthropogenic particle transport applications.