Bio-inspired Chemistry of Novel Metal-Organic Bismuth Compounds

  • Andrews, Philip (Primary Chief Investigator (PCI))
  • Ferrero, Richard (Chief Investigator (CI))
  • Junk, Peter, (Chief Investigator (CI))
  • Kedzierski, Lukasz (Partner Investigator (PI))

Project: Research

Project Description

We intend to investigate new synthetic approaches to unprecedented classes of bismuth compounds to aid
in the establishment of metal-organic compounds of bismuth as non-steroidal anti-inflammatory drugs and
agents to combat Leishmaniasis. We aim to synthesise and fully characterise bismuth derivatives model
compounds for existing non-steroidal anti-inflammatory drugs, and then to the target compounds
themselves, and to evaluate their anti-microbial activity while maintaining anti-inflammatory activity, with a
particular focus on the development of new compounds which have the potential to allow oral or dermal
administration.
StatusFinished
Effective start/end date1/01/1112/05/17

Funding

  • Australian Research Council (ARC): AUD480,000.00
  • Australian Research Council (ARC)
  • Monash University
  • Monash University
  • The Walter and Eliza Hall Institute of Medical Research (WEHI)