Bile Acid and Neurosteroid Signaling to the Nervous System

Research output

Research output per year 2015 2015 2016 2017 2020

• 10 Article
• 1 Chapter (Book)

Research output per year

Research output per year

Search results

• 2020

  Endosomal signaling of delta opioid receptors is an endogenous mechanism and therapeutic target for relief from inflammatory pain

  Jiménez-Vargas, N. N., Gong, J., Wisdom, M. J., Jensen, D. D., Latorre, R., Hegron, A., Teng, S. L., Di Cello, J., Rajasekhar, P., Veldhuis, N. A., Carbone, S., Yu, Y., Lopez, C. L., Polanco, J. J., Canals, M., Reed, D., Lomax, A. E., Schmidt, B. L., Leong, K. W., Vanner, S., & 3 othersHalls, M. L., Bunnett, N. & Poole, D. P., 30 Jun 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 26, p. 15281-15292 12 p.

  Research output: Contribution to journal › Article › Research › peer-review
  77 Citations (Scopus)
• 2018

  Inflammation-associated changes in DOR expression and function in the mouse colon

  Dicello, J. J., Saito, A., Rajasekhar, P., Eriksson, E. M., McQuade, R., Nowell, C., Sebastian, B., Fichna, J., Veldhuis, N. A., Canals, M., Bunnett, N., Carbone, S. E. & Poole, D. P., 1 Oct 2018, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 315, 4, p. G544-G559 39 p.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  File
  23 Citations (Scopus)
• 2017

  Endosomal signaling of the receptor for calcitonin gene-related peptide mediates pain transmission

  Yarwood, R. E., Imlach, W. L., Lieu, T., Veldhuis, N. A., Jensen, D. D., Herenbrink, C. K., Aurelio, L., Cai, Z., Christie, M. J., Poole, D. P., Porter, C. J. H., McLean, P., Hicks, G. A., Geppetti, P., Halls, M. L., Canals, M. & Bunnett, N. W., 14 Nov 2017, In: Proceedings of the National Academy of Sciences of the United States of America. 114, 46, p. 12309-12314 6 p.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  File
  136 Citations (Scopus)

• Neurokinin 1 receptor signaling in endosomes mediates sustained nociception and is a viable therapeutic target for prolonged pain relief

  Jensen, D. D., Lieu, T., Halls, M. L., Veldhuis, N. A., Imlach, W. L., Mai, Q. N., Poole, D. P., Quach, T., Aurelio, L., Conner, J., Klein Herenbrink, C., Barlow, N., Simpson, J. S., Scanlon, M. J., Graham, B., McCluskey, A., Robinson, P. J., Escriou, V., Nassini, R., Materazzi, S., & 6 othersGeppetti, P., Hicks, G. A., Christie, M. J., Porter, C. J. H., Canals, M. & Bunnett, N. W., 31 May 2017, In: Science Translational Medicine. 9, 392, 15 p., aal3447.

  Research output: Contribution to journal › Article › Research › peer-review
  166 Citations (Scopus)
• 2016

  Distribution and trafficking of the μ-opioid receptor in enteric neurons of the guinea pig

  Lay, J., Carbone, S. E., Dicello, J. J., Bunnett, N., Canals, M. & Poole, D. P., 1 Aug 2016, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 311, 2, p. G252-G266 15 p.

  Research output: Contribution to journal › Article › Research › peer-review
  22 Citations (Scopus)

• Neurotensin-induced miR-133α expression regulates neurotensin receptor 1 recycling through its downstream target aftiphilin

  Law, I. K. M., Jensen, D., Bunnett, N. W. & Pothoulakis, C., 23 Feb 2016, In: Scientific Reports. 6, 14 p., 22195.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  File
  10 Citations (Scopus)
• 2015

  Fatty acid-binding proteins 1 and 2 differentially modulate the activation of peroxisome proliferator-activated receptor alpha in a ligand-selective manner

  Hughes, M. L. R., Liu, B., Halls, M. L., Wagstaff, K. M., Patil, R., Velkov, T., Jans, D. A., Bunnett, N. W., Scanlon, M. & Porter, C. J., 2015, In: Journal of Biological Chemistry. 290, 22, p. 13895 - 13906 12 p.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  File
  49 Citations (Scopus)

• Neutrophil elastase activates protease-activated receptor-2 (PAR2) and transient receptor potential vanilloid 4 (TRPV4) to cause inflammation and pain

  Zhao, P., Lieu, T. M., Barlow, N., Sostegni, S., Haerteis, S., Korbmacher, C., Liedtke, W., Jimenez-Vargas, N. N., Vanner, S. & Bunnett, N. W., 2015, In: Journal of Biological Chemistry. 290, 22, p. 13875 - 13887 13 p.

  Research output: Contribution to journal › Article › Research › peer-review
  140 Citations (Scopus)

• P2Y₁ receptor activation of the TRPV4 ion channel enhances purinergic signaling in satellite glial cells

  Rajasekhar, P., Poole, D. P., Liedtke, W., Bunnett, N. W. & Veldhuis, N. A., 2015, In: Journal of Biological Chemistry. 290, 48, p. 29051-29062 12 p.

  Research output: Contribution to journal › Article › Research › peer-review
  39 Citations (Scopus)

• Sensitisation of TRPV4 by PAR₂ is independent of intracellular calcium signalling and can be mediated by the biased agonist neutrophil elastase

  Sostegni, S., Diakov, A., McIntyre, P., Bunnett, N., Korbmacher, C. & Haerteis, S., 2015, In: Pflügers Archiv European Journal of Physiology. 467, 4, p. 687-701 15 p.

  Research output: Contribution to journal › Article › Research › peer-review
  15 Citations (Scopus)