Biased allosteric modulators of metabotropic glutamate receptors: novel therapeutic targets for CNS disorders

Gregory, Karen (Primary Chief Investigator (PCI))

Drug Discovery Biology

Project: Research

Status	Finished
Effective start/end date	1/01/15 → 31/12/18

Funding

National Health & Medical Research Council (NHMRC): AUD591,806.70
National Health & Medical Research Council (NHMRC)

Related content

Research Output

Biased allosteric agonism and modulation of metabotropic glutamate receptor 5: implications for optimizing preclinical neuroscience drug discovery

Research output: Contribution to journal › Article › Research › peer-review

Molecular insights into allosteric modulation of Class C G protein-coupled receptors

Research output: Contribution to journal › Review Article › Research › peer-review

Kinetic and system bias as drivers of metabotropic glutamate receptor 5 allosteric modulator pharmacology

Research output: Contribution to journal › Article › Research › peer-review

Molecular insights into metabotropic glutamate receptor allosteric modulations

Research output: Contribution to journal › Short Survey › Research › peer-review

Neurobiological insights and novel therapeutic opportunities for CNS disorders from mGlu receptor allosteric and biased modulation

Research output: Contribution to journal › Review Article › Research › peer-review