Biased allosteric modulators of metabotropic glutamate receptors: novel therapeutic targets for CNS disorders

Gregory, Karen (Primary Chief Investigator (PCI))

Drug Discovery Biology

Project: Research

Status	Finished
Effective start/end date	1/01/15 → 31/12/18

Funding

NHMRC - National Health and Medical Research Council (Australia): A$591,806.70

7 Article
3 Review Article
1 Short Survey

International Union of Basic and Clinical Pharmacology. CXI. Pharmacology, Signaling, and Physiology of Metabotropic Glutamate Receptors
Gregory, K. J. & Goudet, C., Jan 2021, In: Pharmacological Reviews. 73, 1, p. 521-569 49 p.
Research output: Contribution to journal › Review Article › Other › peer-review

Open Access

43 Citations (Scopus)
Positive Allosteric Modulators of Metabotropic Glutamate Receptor 5 as Tool Compounds to Study Signaling Bias
Arsova, A., Møller, T. C., Hellyer, S. D., Vedel, L., Foster, S. R., Hansen, J. L., Bräuner-Osborne, H. & Gregory, K. J., 1 May 2021, In: Molecular Pharmacology. 99, 5, p. 328-341 14 p.
Research output: Contribution to journal › Article › Research › peer-review

Open Access
File

9 Citations (Scopus)
Detailed In Vitro Pharmacological Characterization of Clinically Tested Negative Allosteric Modulators of the Metabotropic Glutamate Receptor 5
Arsova, A., Møller, T. C., Vedel, L., Hansen, J. L., Foster, S. R., Gregory, K. J. & Bräuner-Osborne, H., 1 Jul 2020, In: Molecular Pharmacology. 98, 1, p. 49-60 12 p.
Research output: Contribution to journal › Article › Research › peer-review

Open Access
File

17 Citations (Scopus)