Australian Sea Anemone Venoms: Bioprospecting & Evolution

  • Norton, Raymond (Primary Chief Investigator (PCI))
  • Purcell, Anthony (Chief Investigator (CI))
  • Hooper, John (Partner Investigator (PI))
  • O'Hara, Tim (Partner Investigator (PI))
  • Papenfuss, Anthony (Partner Investigator (PI))

Project: Research

Project Description

Australian sea anemones are a highly promising and largely unexplored source of peptides and proteins with potential therapeutic and diagnostic applications. This project will evaluate this potential by undertaking transcriptomic analyses of a number species of anemones from Australian waters and identifying peptides and proteins in their venoms by mass spectrometry. It will also demonstrate the value of transcriptomics in informing taxonomic classification of anemones. In addition this project will assess toxin diversity within and between
species based on nematocyst function from specific tissue sources and provide a clearer understanding of the evolution of venoms in Australian Actiniaria.
StatusFinished
Effective start/end date29/12/1531/01/18

Funding

  • Australian Research Council (ARC): AUD174,000.00
  • Australian Research Council (ARC)
  • Monash University
  • Museums Victoria
  • Queensland Museum
  • The Walter and Eliza Hall Institute of Medical Research (WEHI)