Attenuating severe infections in chronic inflammatory diseases through modulation of transforming growth factor-B activity

Pirfenidone Mitigates Transforming Growth Factor-β-induced Inflammation after Viral Infection

Thomas, B. J., Kan-O, K., Gantier, M. P., Simpson, I., Chitty, J. G., Lam, M., Dousha, L., Gottschalk, T. A., Lawlor, K. E., Tate, M. D., Ruwanpura, S., Seow, H. J., Loveland, K. L., Deshpande, S., Li, X., Hamza, K., King, P. T., Elias, J. A., Vlahos, R. & Bourke, J. E. & 1 others, Bardin, P. G., Oct 2025, In: American Journal of Respiratory Cell and Molecular Biology. 73, 4, p. 545-558 14 p.

Research output: Contribution to journal › Article › Research › peer-review

Pharmacological inhibition of TBK1/IKKε blunts immunopathology in a murine model of SARS-CoV-2 infection

Ullah, T. R. (Leading Author), Johansen, M. D. (Leading Author), Balka, K. R., Ambrose, R. L., Gearing, L. J., Roest, J., Vivian, J. P., Sapkota, S., Jayasekara, W. S. N., Wenholz, D. S., Aldilla, V. R., Zeng, J., Miemczyk, S., Nguyen, D. H., Hansbro, N. G., Venkatraman, R., Kang, J. H., Pang, E. S., Thomas, B. J. & Alharbi, A. S. & 13 others, Rezwan, R., O’Keeffe, M., Donald, W. A., Ellyard, J. I., Wong, W., Kumar, N., Kile, B. T., Vinuesa, C. G., Kelly, G. E., Laczka, O. F., Hansbro, P. M. (Leading Author), De Nardo, D. (Leading Author) & Gantier, M. P. (Leading Author), Dec 2023, In: Nature Communications. 14, 1, 13 p., 5666.

Research output: Contribution to journal › Article › Research › peer-review

Genistein Targets STING-Driven Antiviral Responses

Ullah, T. R., Balka, K. R., Ambrose, R. L., Pépin, G., Wilce, M. C. J., Wilce, J. A., Thomas, B. J., De Nardo, D., Williams, B. R. G. & Gantier, M. P., Jul 2022, In: mBio. 13, 4, 6 p.

Research output: Contribution to journal › Article › Research › peer-review