Attenuating severe infections in chronic inflammatory diseases through modulation of transforming growth factor-B activity

Bardin, Philip (Primary Chief Investigator (PCI))
Gantier, Michael (Chief Investigator (CI))
Elias, Jack (Chief Investigator (CI))
Loveland, Katherine (Chief Investigator (CI))

Project: Research

Status	Finished
Effective start/end date	1/01/17 → 31/12/21

Funding

National Health and Medical Research Council (NHMRC) (Australia): A$611,793.00

7 Article

Pharmacological inhibition of TBK1/IKKε blunts immunopathology in a murine model of SARS-CoV-2 infection
Ullah, T. R., Johansen, M. D., Balka, K. R., Ambrose, R. L., Gearing, L. J., Roest, J., Vivian, J. P., Sapkota, S., Jayasekara, W. S. N., Wenholz, D. S., Aldilla, V. R., Zeng, J., Miemczyk, S., Nguyen, D. H., Hansbro, N. G., Venkatraman, R., Kang, J. H., Pang, E. S., Thomas, B. J., Alharbi, A. S., & 13 othersRezwan, R., O’Keeffe, M., Donald, W. A., Ellyard, J. I., Wong, W., Kumar, N., Kile, B. T., Vinuesa, C. G., Kelly, G. E., Laczka, O. F., Hansbro, P. M., De Nardo, D. & Gantier, M. P., Dec 2023, In: Nature Communications. 14, 1, 13 p., 5666.
Research output: Contribution to journal › Article › Research › peer-review

Open Access

5 Citations (Scopus)
Genistein Targets STING-Driven Antiviral Responses
Ullah, T. R., Balka, K. R., Ambrose, R. L., Pépin, G., Wilce, M. C. J., Wilce, J. A., Thomas, B. J., De Nardo, D., Williams, B. R. G. & Gantier, M. P., Jul 2022, In: mBio. 13, 4, 6 p.
Research output: Contribution to journal › Article › Research › peer-review

Open Access

7 Citations (Scopus)
Pharmacological Targeting of STING-Dependent IL-6 Production in Cancer Cells
Al-Asmari, S. S., Rajapakse, A., Ullah, T. R., Pépin, G., Croft, L. V. & Gantier, M. P., 11 Jan 2022, In: Frontiers in Cell and Developmental Biology. 9, 11 p., 709618.
Research output: Contribution to journal › Article › Research › peer-review

Open Access

10 Citations (Scopus)

Animal Research Platform (MARP)
Christine Findlay (Manager)
Faculty of Medicine Nursing and Health Sciences Research Platforms
Facility/equipment: Facility
Histology Platform
Camilla Cohen (Manager)
Faculty of Medicine Nursing and Health Sciences Research Platforms
Facility/equipment: Facility
MHTP Medical Genomics Facility
Trevor Wilson (Manager)
Hudson Institute - Department of Molecular and Translational Science
Facility/equipment: Facility