Project Details
Project Description
In this project we will test the capacity of miniature human kidney tissues ‘organoids’ to model kidney injury and replicate the early sequence of events that initiates a fibrotic response in humans. If successful, our human kidney organoid model will provide a new platform to accelerate the development of antifibrotic therapies to retain renal function in patients suffering from chronic kidney disease.
| Status | Finished |
|---|---|
| Effective start/end date | 30/06/21 → 1/08/24 |
Keywords
- Fibrosis
- Disease modelling
- Kidney organoids
- Directed differentiation
- Chronic kidney disease
- Acute kidney injury