An investigation into metabolic competition between host and pathogen in infection.

Traven, Ana (Primary Chief Investigator (PCI))
Naderer, Thomas (Associate Investigator (AI))
McConville, Malcolm (Associate Investigator (AI))
Beilharz, Traude (Associate Investigator (AI))
Hickey, Michael (Associate Investigator (AI))

University of Melbourne

Project: Research

Status	Finished
Effective start/end date	1/01/19 → 31/12/22

Funding

National Health and Medical Research Council (NHMRC) (Australia): A$645,788.00

4 Article
1 Review Article

Disruption of Iron Homeostasis and Mitochondrial Metabolism Are Promising Targets to Inhibit Candida auris
Simm, C., Weerasinghe, H., Thomas, D. R., Harrison, P. F., Newton, H. J., Beilharz, T. H. & Traven, A., Apr 2022, In: Microbiology Spectrum. 10, 2, 19 p., e0010022.
Research output: Contribution to journal › Article › Research › peer-review

Open Access

2 Citations (Scopus)
The escape of Candida albicans from macrophages is enabled by the fungal toxin candidalysin and two host cell death pathways
Olivier, F. A. B., Hilsenstein, V., Weerasinghe, H., Weir, A., Hughes, S., Crawford, S., Vince, J. E., Hickey, M. J. & Traven, A., 20 Sep 2022, In: Cell Reports. 40, 12, 25 p., 111374.
Research output: Contribution to journal › Article › Research › peer-review

Open Access

1 Citation (Scopus)
Immunometabolism in fungal infections: the need to eat to compete
Weerasinghe, H. & Traven, A., Dec 2020, In: Current Opinion in Microbiology. 58, p. 32-40 9 p.
Research output: Contribution to journal › Review Article › Research › peer-review

Open Access
File

18 Citations (Scopus)

Animal Research Platform (MARP)
Christine Findlay (Manager)
Faculty of Medicine Nursing and Health Sciences Research Platforms
Facility/equipment: Facility
Bioinformatics Platform
Deanna Deveson (Manager)
Faculty of Medicine Nursing and Health Sciences Research Platforms
Facility/equipment: Facility
Monash Micro Imaging
Stephen Firth (Manager), Alex Fulcher (Operator), Oleks Chernyavskiy (Operator), Margaret Rzeszutek (Other), David Potter (Manager), Volker Hilsenstein (Operator), Juan Nunez-Iglesias (Other), Stephen Cody (Manager), Irena Carmichael (Operator), Betty Kouskousis (Other), Sarah Creed (Manager) & Giulia Ballerin (Operator)
Faculty of Medicine Nursing and Health Sciences Research Platforms
Facility/equipment: Facility