Allosteric modulation of GPCR-mediated intracellular signalling in human embryonic stem cell derived cardiomyocytes.

Project: Research

Status	Finished
Effective start/end date	1/01/08 → 30/09/12

Role of the second extracellular loop of the adenosine A₁ receptor on allosteric modulator binding, signaling, and cooperativity
Nguyen, A. T. N., Vecchio, E. A., Thomas, T., Nguyen, T. D., Aurelio, L., Scammells, P. J., White, P. J., Sexton, P. M., Gregory, K. J., May, L. T. & Christopoulos, A., 1 Dec 2016, In: Molecular Pharmacology. 90, 6, p. 715-725 11 p.
Research output: Contribution to journal › Article › Research › peer-review

35 Citations (Scopus)
Structure-activity analysis of biased agonism at the human adenosine A₃ receptor
Baltos, J-A., Paoletta, S., Nguyen, A. T. N., Gregory, K. J., Tosh, D. K., Christopoulos, A., Jacobson, K. A. & May, L. T., 1 Jul 2016, In: Molecular Pharmacology. 90, 1, p. 12-22 11 p.
Research output: Contribution to journal › Article › Research › peer-review

35 Citations (Scopus)
The evolving pharmacology of GPCRs
May, L. T., Holliday, N. D. & Hill, S. J., 15 Jul 2010, GPCR Molecular Pharmacology and Drug Targeting: Shifting Paradigms and New Directions. Gilchrist, A. (ed.). Hoboken NJ USA: John Wiley & Sons, p. 27-60 34 p.
Research output: Chapter in Book/Report/Conference proceeding › Chapter (Book) › Research › peer-review

3 Citations (Scopus)

Project Details