Adenosine Receptor Context-Specific Biased Agonism to Treat Ischaemic Heart Disease

Research output

Research output per year 2021 2021 2022 2023 2023

• 7 Review Article
• 5 Article

Research output per year

Research output per year

Search results

• 2023

  Structure-based virtual screening discovers potent and selective adenosine A₁ receptor antagonists

  Matricon, P., Nguyen, A. TN., Vo, D. D., Baltos, J. A., Jaiteh, M., Luttens, A., Kampen, S., Christopoulos, A., Kihlberg, J., May, L. T. & Carlsson, J., 5 Sept 2023, In: European Journal of Medicinal Chemistry. 257, 115419.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access
  1 Citation (Scopus)
• 2022

  Examining the Role of the Linker in Bitopic N⁶-Substituted Adenosine Derivatives Acting as Biased Adenosine A₁Receptor Agonists

  Awalt, J. K., Nguyen, A. T. N., Fyfe, T. J., Thai, B. S., White, P. J., Christopoulos, A., Jörg, M., May, L. T. & Scammells, P. J., 21 Jun 2022, In: Journal of Medicinal Chemistry. 65, 13, p. 9076–9095 20 p.

  Research output: Contribution to journal › Article › Research › peer-review
• 2021

  Development and Application of Subtype-Selective Fluorescent Antagonists for the Study of the Human Adenosine A₁Receptor in Living Cells

  Comeo, E., Trinh, P., Nguyen, A. T., Nowell, C. J., Kindon, N. D., Soave, M., Stoddart, L. A., White, J. M., Hill, S. J., Kellam, B., Halls, M. L., May, L. T. & Scammells, P. J., 16 Mar 2021, In: Journal of Medicinal Chemistry. 64, 10, p. 6670–6695 26 p.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access
  6 Citations (Scopus)

• Development of Covalent, Clickable Probes for Adenosine A₁and A₃Receptors

  Trinh, P. N. H., Chong, D. J. W., Leach, K., Hill, S. J., Tyndall, J. D. A., May, L. T., Vernall, A. J. & Gregory, K. J., 14 Jun 2021, In: Journal of Medicinal Chemistry. 64, 12, p. 8161–8178 18 p.

  Research output: Contribution to journal › Article › Research › peer-review
  6 Citations (Scopus)

• Positive allosteric mechanisms of adenosine A₁ receptor-mediated analgesia

  Draper-Joyce, C. J., Bhola, R., Wang, J., Bhattarai, A., Nguyen, A. T. N., Cowie-Kent, I., O’Sullivan, K., Chia, L. Y., Venugopal, H., Valant, C., Thal, D. M., Wootten, D., Panel, N., Carlsson, J., Christie, M. J., White, P. J., Scammells, P., May, L. T., Sexton, P. M., Danev, R., & 4 othersMiao, Y., Glukhova, A., Imlach, W. L. & Christopoulos, A., 23 Sept 2021, In: Nature. 597, p. 571–576 25 p.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access
  54 Citations (Scopus)