Accelerated phase I trial of targeted and tunable SARS-Cov-2 spike protein receptor binding domain recombinant protein and mRNA vaccines

Nolan, Terry M. (Primary Chief Investigator (PCI))
Godfrey, Dale Ian (Chief Investigator (CI))
Purcell, Damian F.J. (Chief Investigator (CI))
Pouton, Colin (Chief Investigator (CI))
Jackson, David (Chief Investigator (CI))
Simpson, Prof Julie (Chief Investigator (CI))
Rockman, Steven P. (Chief Investigator (CI))
Braat, Miss Sabine (Chief Investigator (CI))
Ratnam, Dr Irani (Chief Investigator (CI))

Drug Delivery Disposition & Dynamics

Project: Research

Project Description

MRFF application funded in the following round: 2020 Rare Cancers Rare Diseases and Unmet Need - COVID 19

Short title	Accelerated phase I trial of SARS-CoV-2 vaccines
Status	Finished
Effective start/end date	1/09/21 → 30/08/23

Keywords

COVID-19
Vaccine
Clinical trial

1 Article

Interim results from a phase I randomized, placebo-controlled trial of novel SARS-CoV-2 beta variant receptor-binding domain recombinant protein and mRNA vaccines as a 4th dose booster
Nolan, T. M., Deliyannis, G., Griffith, M., Braat, S., Allen, L. F., Audsley, J., Chung, A. W., Ciula, M., Gherardin, N. A., Giles, M. L., Gordon, T. P., Grimley, S. L., Horng, L., Jackson, D. C., Juno, J. A., Kedzierska, K., Kent, S. J., Lewin, S. R., Littlejohn, M., McQuilten, H. A., & 24 othersMordant, F. L., Nguyen, T. H. O., Soo, V. P., Price, B., Purcell, D. F. J., Ramanathan, P., Redmond, S. J., Rockman, S., Ruan, Z., Sasadeusz, J., Simpson, J. A., Subbarao, K., Fabb, S. A., Payne, T. J., Takanashi, A., Tan, C. W., Torresi, J., Wang, J. J., Wang, L. F., Al-Wassiti, H., Wong, C. Y., Zaloumis, S., Pouton, C. W. & Godfrey, D. I., Dec 2023, In: EBioMedicine. 98, 17 p., 104878.
Research output: Contribution to journal › Article › Research › peer-review

Open Access

4 Citations (Scopus)