A translational framework for discovering novel solutions for drug resistance in acute myeloid leukaemia

Project: Research

Status	Relinquished
Effective start/end date	1/01/20 → 9/01/23

Acquired mutations in BAX confer resistance to BH3-mimetic therapy in acute myeloid leukemia
Moujalled, D. M., Brown, F. C., Chua, C. C., Dengler, M. A., Pomilio, G., Anstee, N. S., Litalien, V., Thompson, E., Morley, T., MacRaild, S., Tiong, I. S., Morris, R., Dun, K., Zordan, A., Shah, J., Banquet, S., Halilovic, E., Morris, E., Herold, M. J., Lessene, G., & 5 othersAdams, J. M., Huang, D. C. S., Roberts, A. W., Blombery, P. & Wei, A. H., 9 Feb 2023, In: Blood. 141, 6, p. 634–644 11 p.
Research output: Contribution to journal › Article › Research › peer-review

Open Access

43 Citations (Scopus)
Intact TP-53 function is essential for sustaining durable responses to BH3-mimetic drugs in leukemias
Thijssen, R., Diepstraten, S. T., Moujalled, D., Chew, E., Flensburg, C., Shi, M. X., Dengler, M. A., Litalien, V., MacRaild, S., Chen, M., Anstee, N. S., Reljić, B., Gabriel, S. S., Djajawi, T. M., Riffkin, C. D., Aubrey, B. J., Chang, C., Tai, L., Xu, Z., Morley, T., & 16 othersPomilio, G., Bruedigam, C., Kallies, A., Stroud, D. A., Bajel, A., Kluck, R. M., Lane, S. W., Schoumacher, M., Banquet, S., Majewski, I. J., Strasser, A., Roberts, A. W., Huang, D. C. S., Brown, F. C., Kelly, G. L. & Wei, A. H., 20 May 2021, In: Blood. 137, 20, p. 2721-2735 15 p.
Research output: Contribution to journal › Article › Research › peer-review

86 Citations (Scopus)

Project Details