A Systems Approach to the Adaptive Immune Response

Hodgkin, Philip D. (Primary Chief Investigator (PCI))
Corcoran, Lynn M. (Chief Investigator (CI))
Tarlinton, David (Chief Investigator (CI))
Belz, Gabrielle (Chief Investigator (CI))
Nutt, Stephen Laurence (Chief Investigator (CI))

Immunology Alfred Hospital

Project: Research

Status	Finished
Effective start/end date	1/01/14 → 31/12/18

15 Article

Targeting BMI-1 in B cells restores effective humoral immune responses and controls chronic viral infection
Di Pietro, A., Polmear, J., Cooper, L., Damelang, T., Hussain, T., Hailes, L., O’Donnell, K., Udupa, V., Mi, T., Preston, S., Shtewe, A., Hershberg, U., Turner, S. J., La Gruta, N. L., Chung, A. W., Tarlinton, D. M., Scharer, C. D. & Good-Jacobson, K. L., Jan 2022, In: Nature Immunology. 23, 1, p. 86-98 13 p.
Research output: Contribution to journal › Article › Research › peer-review

Open Access

24 Citations (Scopus)
Loss of Bcl-G, a Bcl-2 family member, augments the development of inflammation-associated colorectal cancer
Nguyen, P. M., Dagley, L. F., Preaudet, A., Lam, N., Giam, M., Fung, K. Y., Aizel, K., van Duijneveldt, G., Tan, C. W., Hirokawa, Y., Yip, H. Y. K., Love, C. G., Poh, A. R., Cruz, A. D., Burstroem, C., Feltham, R., Abdirahman, S. M., Meiselbach, K., Low, R. R. J. & Palmieri, M. & 6 others, Ernst, M., Webb, A. I., Burgess, T., Sieber, O. M., Bouillet, P. & Putoczki, T. L., Feb 2020, In: Cell Death and Differentiation. 27, 2, p. 742-757 16 p.
Research output: Contribution to journal › Article › Research › peer-review

Open Access
File

8 Citations (Scopus)
A divergent transcriptional landscape underpins the development and functional branching of MAIT cells
Koay, H. F., Su, S., Amann-Zalcenstein, D., Daley, S. R., Comerford, I., Miosge, L., Whyte, C. E., Konstantinov, I. E., d'Udekem, Y., Baldwin, T., Hickey, P. F., Berzins, S. P., Mak, J. Y. W., Sontani, Y., Roots, C. M., Sidwell, T., Kallies, A., Chen, Z., Nüssing, S. & Kedzierska, K. & 11 others, Mackay, L. K., McColl, S. R., Deenick, E. K., Fairlie, D. P., McCluskey, J., Goodnow, C. C., Ritchie, M. E., Belz, G. T., Naik, S. H., Pellicci, D. G. & Godfrey, D. I., 22 Nov 2019, In: Science Immunology. 4, 41, 16 p., 6039.
Research output: Contribution to journal › Article › Research › peer-review

78 Citations (Scopus)

Animal Research Platform (MARP)
Findlay, C. (Manager)
Faculty of Medicine Nursing and Health Sciences Research Platforms
Facility/equipment: Facility
Bioinformatics Platform
Deveson, D. (Manager)
Faculty of Medicine Nursing and Health Sciences Research Platforms
Facility/equipment: Facility
Centre for Electron Microscopy (MCEM)
Sorrell, F. (Manager) & Miller, P. (Manager)
Office of the Vice-Provost (Research and Research Infrastructure)
Facility/equipment: Facility

A Systems Approach to the Adaptive Immune Response

Project Details

Research output

Targeting BMI-1 in B cells restores effective humoral immune responses and controls chronic viral infection

Loss of Bcl-G, a Bcl-2 family member, augments the development of inflammation-associated colorectal cancer

A divergent transcriptional landscape underpins the development and functional branching of MAIT cells

Equipment

Animal Research Platform (MARP)

Bioinformatics Platform

Centre for Electron Microscopy (MCEM)