A study of the interrelationships between drug release and polymer biodegradation of novel drug-polymerconjugates (DPCs)

  • Davis, Thomas (Primary Chief Investigator (PCI))
  • Prankerd, Richard, (Chief Investigator (CI))
  • Whittaker, Mikey (Chief Investigator (CI))
  • Donohue, Andrew C. (Partner Investigator (PI))
  • Tait, Russell (Partner Investigator (PI))

Project: Research

Project Description

This proposal aims to carry out a comprehensive investigation of novel polyurethane based drug-polymer
conjugates. By utilizing a modular approach for assembling the drug-conjugated devices, a variety of
components will be scrutinized which result in different polymer biodegradation characteristics, drug release
rates and physical properties. These studies will provide key knowledge about the inter-relationships
between the key elements so that each can be precisely tailored in order to meet the specific requirements
of a particular biological site and drug. Ultimately, these studies will lead to the production of new drugcarrier
polymer devices suitable for the treatment of illnesses and diseases not currently catered for by
PolyActiva.
StatusFinished
Effective start/end date3/10/1430/06/17

Funding

  • Australian Research Council (ARC): AUD450,000.00
  • PolyActiva Pty Ltd: AUD263,900.00