A structural understanding of class B G protein-coupled receptor function

Sexton, Patrick (Primary Chief Investigator (PCI))
Kobilka, Brian, (Chief Investigator (CI))
Skiniotis, Georgios (Chief Investigator (CI))
Furness, Sebastian (Chief Investigator (CI))

Drug Discovery Biology

Project: Research

Status	Active
Effective start/end date	1/01/17 → 31/12/21

Funding

National Health & Medical Research Council (NHMRC): AUD1,289,570.00

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Research Output

Characterization of signalling and regulation of common calcitonin receptor splice variants and polymorphisms

Research output: Contribution to journal › Article › Research › peer-review

Phase-plate cryo-EM structure of a biased agonistbound human GLP-1 receptor-Gs complex

Research output: Contribution to journal › Article › Research › peer-review

Cryo-EM structure of the active, G_s-protein complexed, human CGRP receptor

Research output: Contribution to journal › Article › Research › peer-review

Equipment

Cryo-Electron Microscopy

Facility/equipment: Facility

Micro Imaging

Facility/equipment: Facility