A structural understanding of calcitonin gene-related peptide and adrenomedullin function

Project: Research

Status	Active
Effective start/end date	1/01/19 → 31/12/23

National Health and Medical Research Council (NHMRC) (Australia): AUD1,162,535.00

Routine sub-2.5 Å cryo-EM structure determination of GPCRs
Danev, R., Belousoff, M., Liang, Y. L., Zhang, X., Eisenstein, F., Wootten, D. & Sexton, P. M., Dec 2021, In: Nature Communications. 12, 1, 10 p., 4333.
Research output: Contribution to journal › Article › Research › peer-review

Open Access

4 Citations (Scopus)
Structure and dynamics of the CGRP receptor in apo and peptide-bound forms
Josephs, T. M., Belousoff, M. J., Liang, Y. L., Piper, S. J., Cao, J., Garama, D. J., Leach, K., Gregory, K. J., Christopoulos, A., Hay, D. L., Danev, R., Wootten, D. & Sexton, P. M., 9 Apr 2021, In: Science. 372, 6538, 11 p., eabf7258.
Research output: Contribution to journal › Article › Research › peer-review

19 Citations (Scopus)
Structure and Dynamics of Adrenomedullin Receptors AM₁ and AM₂ Reveal Key Mechanisms in the Control of Receptor Phenotype by Receptor Activity-Modifying Proteins
Liang, Y. L., Belousoff, M. J., Fletcher, M. M., Zhang, X., Khoshouei, M., Deganutti, G., Koole, C., Furness, S. G. B., Miller, L. J., Hay, D. L., Christopoulos, A., Reynolds, C. A., Danev, R., Wootten, D. & Sexton, P. M., 10 Apr 2020, In: ACS Pharmacology & Translational Science. 3, 2, p. 263-284 22 p.
Research output: Contribution to journal › Article › Research › peer-review

36 Citations (Scopus)

Project Details