A randomised controlled trial to prevent eczema, food allergy and sensitisation using a skin barrier improvement strategy

  • Lowe, Adrian J (Primary Chief Investigator (PCI))
  • Tang, Mimi L K (Chief Investigator (CI))
  • Dharmage, Shyamali Chandrika (Chief Investigator (CI))
  • Matheson, Melanie C (Chief Investigator (CI))
  • Su, John (Chief Investigator (CI))

Project: Research

Project Details

Project Description

A prospective cohort study to randomise 760 children with a family history of allergic disease to either receive twice daily application of EpiCeram, a
novel skin barrier repair treatment, or standard skin care to test if building the infant skin barrier in the first six months of life can reduce a) the true incidence
of eczema, not only during the treatment period, but also in the six months after treatment cessation b) the development of food allergy and allergic
sensitisation. Primary outcomes will be assessed by a blinded assessor. If successful, this trial will have wide spread implications for infant care, as well as
reducing the burden of allergic diseases in our community.
Effective start/end date1/01/1731/12/20