A global approach to structure, assembly and function of yeast mitochondrial ATP synthase

  • Devenish, Rodney (Primary Chief Investigator (PCI))
  • Nagley, Phillip (Chief Investigator (CI))

Project: Research

Project Details

Project Description

ATP synthase is responsible for the synthesis of the ubiquitous energy substance ATP in living cells. This multisubunit enzyme complex is a molecular rotatory motor whose mechanism relies on functional dynamic interactions of the component protein subunits of the complex. Using a combination of powerful and sophisticated molecular biology techniques the functional and dynamic contacts made by subunits within the complex, or between ATP synthase and other enzyme complex involved in energy production (including other ATP synthase complexes) will be investigated. New and significant insights into one of the most fundamental and challenging enzymes of life will be obtained.
Effective start/end date1/01/0231/12/04


  • Australian Research Council (ARC): AUD375,000.00