The ability to image cells in action at the highest possible resolution is critical to efforts to understand living systems. The last decade has witnessed a microscopy revolution, providing views of cellular life that were unimaginable only a few years ago. We request LIEF funding to establish a Cellular NanoImaging Facility. This capability will enable us to investigate molecular 'machines' in action, and to probe structural and functional dynamics at the subcellular level. We will capture the three spatial dimensions at unprecendented resolution, follow changes with time as a fourth dimension, and also probe protein-protein interactions - effectively giving us a 5D view of cellular life.
|Effective start/end date||1/01/12 → 31/12/12|
- Australian Research Council (ARC)