1990 …2021
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Research Output 1990 2019

2007

Avenues for Pharmacogenetic Research in ADHD

Barry, E., Hawi, Z. & Kirley, A., 2007, Handbook of Attention Deficit Hyperactivity Disorder. Fitzgerald, M., Bellgrove, M. & Gill, M. (eds.). John Wiley & Sons, p. 355-371 16 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

44 Citations (Scopus)

Dopaminergic genotype biases spatial attention in healthy children

Bellgrove, MA., Chambers, C. D., Johnson, K. A., Daibhis, A., Daly, M., Barry, E., Hawi, Z., Lambert, D., Gill, M. & Robertson, I. H., 2007, In : Molecular Psychiatry. 12, 8, p. 786-792 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Molecular Genetic aspects of Attention deficit Hyperactivity Disorder

Hawi, Z. & Lowe, N., 2007, Handbook of Attention Deficit Hyperactivity Disorder. Fitzgerald, M., Bellgrove, M. & Gill, M. (eds.). 1 ed. The U.K: John Wiley & Sons, Vol. 1. p. 129-147 18 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

17 Citations (Scopus)

No association between TPH2 gene polymorphisms and ADHD in a UK sample

Sheehan, K., Hawi, Z., Gill, M. & Kent, L., 29 Jan 2007, In : Neuroscience Letters. 412, 2, p. 105-107 3 p.

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

Protein kinase C-beta 1 gene variants are not associated with autism in the Irish population

Yang, M. S., Cochrane, L., Conroy, J., Hawi, Z., Fitzgerald, M. F., Gallagher, L. & Gill, M., Feb 2007, In : Psychiatric Genetics. 17, 1, p. 39-41 3 p.

Research output: Contribution to journalArticleResearchpeer-review

2006
6 Citations (Scopus)

An overview of the pharmacogenetics and molecular genetics of ADHD

Lowe, N., Barry, E., Gill, M. & Hawi, Z., Sep 2006, In : Current Pharmacogenomics. 4, 3, p. 231-243 13 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

2 Citations (Scopus)

Erratum: Tryptophan hydroxylase 2 (TPH2) gene variants associated with ADHD (Molecular Psychiatry (2005) 10 (944-949) DOI: 10.1038/sj.mp.4001698)

Sheehan, K., Lowe, N., Kirley, A., Mullins, C., Fitzgerald, M., Gill, M. & Hawi, Z., Feb 2006, In : Molecular Psychiatry. 11, 2, p. 221 1 p.

Research output: Contribution to journalComment / DebateOtherpeer-review

19 Citations (Scopus)

Impaired temporal resolution of visual attention and dopamine beta hydroxylase genotype in attention-deficit/hyperactivity disorder

Bellgrove, M. A., Mattingley, J. B., Hawi, Z., Mullins, C., Kirley, A., Gill, M. & Robertson, I. H., 2006, In : Biological Psychiatry. 60, 10, p. 1039 - 1045 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Reply to Joober and Sengupta [2]

Segurado, R., Hawi, Z. & Gill, M., Oct 2006, In : American Journal of Human Genetics. 79, 4, p. 766-768 3 p.

Research output: Contribution to journalLetterResearchpeer-review

70 Citations (Scopus)

The Cognitive Genetics of Attention Deficit Hyperactivity Disorder (ADHD): Sustained attention as a Candidate Phenotype

Bellgrove, M. A., Hawi, Z., Gill, M. & Robertson, I. H., 2006, In : Cortex. 42, p. 838 - 845 8 p.

Research output: Contribution to journalArticleResearchpeer-review

2005
62 Citations (Scopus)

Association analysis of the monoamine oxidase A and B genes with attention deficit hyperactivity disorder (ADHD) in an Irish sample: Preferential transmission of the MAO-A 941G allele to affected children

Domschke, K., Sheehan, K., Lowe, N., Kirley, A., Mullins, C., O'Sullivan, R., Freitag, C., Becker, T., Conroy, J., Fitzgerald, M., Gill, M. & Hawi, Z., 5 Apr 2005, In : American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 134 B, 1, p. 110-114 5 p.

Research output: Contribution to journalArticleResearchpeer-review

75 Citations (Scopus)

Association between dopamine transporter (DAT1) genotype, left-sided inattention, and an enhanced response to methylphenidate in attention-deficit hyperactivity disorder

Bellgrove, M. A., Hawi, Z., Kirley, A., Fitzgerald, M., Gill, M. & Robertson, I. H., Dec 2005, In : Neuropsychopharmacology. 30, 12, p. 2290-2297 8 p.

Research output: Contribution to journalArticleResearchpeer-review

97 Citations (Scopus)

Association of the paternally transmitted copy of common Valine allele of the Val66Met polymorphism of the brain-derived neurotrophic factor (BDNF) gene with susceptibility to ADHD

Kent, L., Green, E., Hawi, Z., Kirley, A., Dudbridge, F., Lowe, N., Raybould, R., Langley, K., Bray, N., Fitzgerald, M., Owen, M. J., O'Donovan, M. C., Gill, M., Thapar, A. & Craddock, N., Oct 2005, In : Molecular Psychiatry. 10, 10, p. 939-943 5 p.

Research output: Contribution to journalArticleResearchpeer-review

149 Citations (Scopus)

Dissecting the attention deficit hyperactivity disorder (ADHD) phenotype: Sustained attention, response variability and spatial attentional asymmetries in relation to dopamine transporter (DAT1) genotype

Bellgrove, M. A., Hawi, Z., Kirley, A., Gill, M. & Robertson, I. H., 2005, In : Neuropsychologia. 43, 13, p. 1847-1857 11 p.

Research output: Contribution to journalArticleResearchpeer-review

85 Citations (Scopus)

DRD4 gene variants and sustained attention in attention deficit hyperactivity disorder (ADHD): Effects of associated alleles at the VNTR and -521 SNP

Bellgrove, M. A., Hawi, Z., Lowe, N., Kirley, A., Robertson, I. H. & Gill, M., 5 Jul 2005, In : American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 136 B, 1, p. 81-86 6 p.

Research output: Contribution to journalArticleResearchpeer-review

61 Citations (Scopus)

Preferential transmission of paternal alleles at risk genes in attention-deficit/hyperactivity disorder

Hawi, Z., Segurado, R., Conroy, J., Sheehan, K., Lowe, N., Kirley, A., Shields, D., Fitzgerald, M., Gallagher, L. & Gill, M., Dec 2005, In : American Journal of Human Genetics. 77, 6, p. 958-965 8 p.

Research output: Contribution to journalArticleResearchpeer-review

68 Citations (Scopus)

The methionine allele of the COMT polymorphism impairs prefrontal cognition in children and adolescents with ADHD

Bellgrove, M. A., Domschke, K., Hawi, Z., Kirley, A., Mullins, C., Robertson, I. H. & Gill, M., Jun 2005, In : Experimental Brain Research. 163, 3, p. 352-360 9 p.

Research output: Contribution to journalArticleResearchpeer-review

99 Citations (Scopus)

Tryptophan hydroxylase 2 (TPH2) gene variants associated with ADHD

Sheehan, K., Lowe, N., Kirley, A., Mullins, C., Fitzgerald, M., Gill, M. & Hawi, Z., Oct 2005, In : Molecular Psychiatry. 10, 10, p. 944-949 6 p.

Research output: Contribution to journalArticleResearchpeer-review

2004
155 Citations (Scopus)

Joint Analysis of the DRD5 Marker Concludes Association with Attention-Deficit/Hyperactivity Disorder Confined to the Predominantly Inattentive and Combined Subtypes

Lowe, N., Kirley, A., Hawi, Z., Sham, P., Wickham, H., Kratochvil, C. J., Smith, S. D., Lee, S. Y., Levy, F., Kent, L., Middle, F., Rohde, L. A., Roman, T., Tahir, E., Yazgan, Y., Asherson, P., Mil, J., Thapar, A., Payton, A., Todd, R. D. & 12 others, Stephens, T., Ebstein, R. P., Manor, I., Barr, C. L., Wigg, K. G., Sinke, R. J., Buitelaar, J. K., Smalley, S. L., Nelson, S. F., Biederman, J., Faraone, S. V. & Gill, M., Feb 2004, In : American Journal of Human Genetics. 74, 2, p. 348-356 9 p.

Research output: Contribution to journalArticleResearchpeer-review

47 Citations (Scopus)

Multiple marker analysis at the promoter region of the DRD4 gene and ADHD: Evidence of linkage and association with the SNP -616

Lowe, N., Kirley, A., Mullins, C., Fitzgerald, M., Gill, M. & Hawi, Z., 15 Nov 2004, In : American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 131 B, 1, p. 33-37 5 p.

Research output: Contribution to journalArticleResearchpeer-review

21 Citations (Scopus)

No Association between Allelic Variants of HOXA1/HOXB1 and Autism

Gallagher, L., Hawi, Z., Kearney, G., Fitzgerald, M. & Gill, M., 1 Jan 2004, In : American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 124 B, 1, p. 64-67 4 p.

Research output: Contribution to journalArticleResearchpeer-review

58 Citations (Scopus)

Phenotype studies of the DRD4 gene polymorphisms in ADHD: Association with oppositional defiant disorder and positive family history

Kirley, A., Lowe, N., Mullins, C., McCarron, M., Daly, G., Waldman, I., Fitzgerald, M., Gill, M. & Hawi, Z., 15 Nov 2004, In : American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 131 B, 1, p. 38-42 5 p.

Research output: Contribution to journalArticleResearchpeer-review

2003
134 Citations (Scopus)

Association of the 480 bp DAT1 allele with methylphenidate response in a sample of Irish children with ADHD

Kirley, A., Lowe, N., Hawi, Z., Mullins, C., Daly, G., Waldman, I., McCarron, M., O'Donnell, D., Fitzgerald, M. & Gill, M., 15 Aug 2003, In : American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 121 B, 1, p. 50-54 5 p.

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)

Late onset Alzheimer's disease and apolipoprotein association in the Irish population: Relative risk and attributable fraction

Hawi, Z., Sheehan, K., Lynch, A., Evans, I., Lowe, N., Lawlor, B. & Gill, M., Apr 2003, In : Irish Journal of Medical Science. 172, 2, p. 74-76 3 p.

Research output: Contribution to journalArticleResearchpeer-review

109 Citations (Scopus)

Linkage disequilibrium mapping at DAT1, DRD5 and DBH narrows the search for ADHD susceptibility alleles at these loci

Hawi, Z., Lowe, N., Kirley, A., Gruenhage, F., Nöthen, M., Greenwood, T., Kelsoe, J., Fitzgerald, M. F. & Gill, M., 2003, In : Molecular Psychiatry. 8, 3, p. 299-308 10 p.

Research output: Contribution to journalArticleResearchpeer-review

10 Citations (Scopus)

Recent genetic advances in ADHD and diagnostic and therapeutic prospects

Hawi, Z., Kirley, A., Lowe, N., Fitzgerald, M. & Gill, M., Jul 2003, In : Expert Review of Neurotherapeutics. 3, 4, p. 453-464 12 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

2002
81 Citations (Scopus)

Association of DRD4 in children with ADHD and comorbid conduct problems

Holmes, J., Payton, A., Barrett, J., Harrington, R., McGuffin, P., Owen, M., Ollier, W., Worthington, J., Gill, M., Kirley, A., Hawi, Z., Fitzgerald, M., Asherson, P., Curran, S., Mill, J., Gould, A., Taylor, E., Kent, L., Craddock, N. & Thapar, A., 8 Mar 2002, In : American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 114, 2, p. 150-153 4 p.

Research output: Contribution to journalArticleResearchpeer-review

157 Citations (Scopus)

Dopaminergic system genes in ADHD: Toward a biological hypothesis

Kirley, A., Hawi, Z., Daly, G., McCarron, M., Mullins, C., Millar, N., Waldman, I., Fitzgerald, M. & Gill, M., Oct 2002, In : Neuropsychopharmacology. 27, 4, p. 607-619 13 p.

Research output: Contribution to journalArticleResearchpeer-review

124 Citations (Scopus)

Evidence that variation at the serotonin transporter gene influences susceptibility to attention deficit hyperactivity disorder (ADHD): Analysis and pooled analysis

Kent, L., Doerry, U., Hardy, E., Parmar, R., Gingell, K., Hawi, Z., Kirley, A., Lowe, N., Fitzgerald, M., Gill, M. & Craddock, N., 2002, In : Molecular Psychiatry. 7, 8, p. 908-912 5 p.

Research output: Contribution to journalArticleResearchpeer-review

44 Citations (Scopus)

No evidence of linkage or association between the norepinephrine transporter (NET) gene polymorphisms and ADHD in the Irish population [2]

McEvoy, B., Hawi, Z., Fitzgerald, M. & Gill, M., 8 Aug 2002, In : American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 114, 6, p. 665-666 2 p.

Research output: Contribution to journalLetterResearchpeer-review

140 Citations (Scopus)

Serotonergic system and attention deficit hyperactivity disorder (ADHD): A potential susceptibility locus at the 5-HT1B receptor gene in 273 nuclear families from a multi-centre sample

Hawi, Z., Dring, M., Kirley, A., Foley, D., Kent, L., Craddock, N., Asherson, P., Curran, S., Gould, A., Richards, S., Lawson, D., Pay, H., Turic, D., Langley, K., Owen, M., O'Donovan, M., Thapar, A., Fitzgerald, M. & Gill, M., 2002, In : Molecular Psychiatry. 7, 7, p. 718-725 8 p.

Research output: Contribution to journalArticleResearchpeer-review

130 Citations (Scopus)

Synaptosomal-associated protein 25 (SNAP-25) and attention deficit hyperactivity disorder (ADHD): Evidence of linkage and association in the Irish population

Brophy, K., Hawi, Z., Kirley, A., Fitzgerald, M. & Gill, M., 2002, In : Molecular Psychiatry. 7, 8, p. 913-917 5 p.

Research output: Contribution to journalArticleResearchpeer-review

2001

A review of attention deficit hyperactivity disorder and dopamine system candidate

Kirley, A., Hawi, Z., McCarron, M., Mullins, C., Fitzgerald, M. & Gill, M., 8 Oct 2001, In : American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 105, 7, p. 634 1 p.

Research output: Contribution to journalArticleResearchpeer-review

A significant association of serotonin transporter polymorphism haplotypes in attention deficit hyperactivity disorder (ADHD)

Kent, L., Hardy, E., Hawi, Z., Fitzgerald, M., Kirley, A., Gill, M. & Craddock, N., 8 Oct 2001, In : American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 105, 7, p. 574-575 2 p.

Research output: Contribution to journalArticleResearchpeer-review

Attention deficit hyperactivity disorder (ADHD) and 5HT2C receptor: A slight increase in the transmission of Cys23 to ADHD cases

Nugent, E., Hawi, Z., Lowe, N., Kirley, A., Fitzgerald, M. F. & Gill, M., 8 Oct 2001, In : American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 105, 7, p. 637 1 p.

Research output: Contribution to journalArticleResearchpeer-review

34 Citations (Scopus)

Dopa decarboxylase gene polymorphisms and attention deficit hyperactivity disorder (ADHD): No evidence for association in the Irish population

Hawi, Z., Foley, D., Kirley, A., McCarron, M., Fitzgerald, M. & Gill, M., 2001, In : Molecular Psychiatry. 6, 4, p. 420-424 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Haplotype analysis at the DAT1 locus suggests that the variant contributing to ADHD may map to the 3′end of the gene

Hawi, Z. H., Lowe, N. T., Kirley, A., Fitzgerald, M. & Gill, 8 Oct 2001, In : American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 105, 7, p. 573 1 p.

Research output: Contribution to journalArticleResearchpeer-review

New evidence, supporting an association between attention deficit hyperactivity disorder and the DRD5 locus in the IRISH population

Lowe, N. T., Hawi, Z., Kirley, A., Mullins, C., Fitzgerald, M. & Gill, M., 8 Oct 2001, In : American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 105, 7, p. 635 1 p.

Research output: Contribution to journalArticleOtherpeer-review

59 Citations (Scopus)

Nicotinic acetylcholine receptor α4 subunit gene polymorphism and attention deficit hyperactivity disorder

Kent, L., Middle, F., Hawi, Z., Fitzgerald, M., Gill, M., Feehan, C. & Craddock, N., 2001, In : Psychiatric Genetics. 11, 1, p. 37-40 4 p.

Research output: Contribution to journalArticleResearchpeer-review

25 Citations (Scopus)

No association between CHRNA7 microsatellite markers and attention-deficit hyperactivity disorder

Kent, L., Green, E., Holmes, J., Thapar, A., Gill, M., Hawi, Z., Fitzgerald, M., Asherson, P., Curran, S., Mills, J., Payton, A. & Craddock, N., 8 Dec 2001, In : American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 105, 8, p. 686-689 4 p.

Research output: Contribution to journalArticleResearchpeer-review

No association of allelic variant of HOXA1 and autism

Gallagher, L., Hawi, Z., Kearney, G., Fitzgerald, M. F. & Gill, M., 8 Oct 2001, In : American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 105, 7, p. 632 1 p.

Research output: Contribution to journalArticleResearchpeer-review

11 Citations (Scopus)

No evidence of linkage or association between ADHD and DXS7 locus in Irish population

Lowe, N., Hawi, Z., Fitzgerald, M. & Gill, M., 8 May 2001, In : American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 105, 4, p. 394-395 2 p.

Research output: Contribution to journalLetterOtherpeer-review

Serotonergic system and attention deficit hyperactivity disorder (ADHD): A potential susceptibility locus at the 5-HT1B receptor gene in 271 nuclear families from a multi-centre sample

Hawi, Z., Dring, M., Kirley, A., Kent, L., Asherson, P., Thapar, A. & Gill, M., 8 Oct 2001, In : American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 105, 7, p. 636 1 p.

Research output: Contribution to journalArticleResearchpeer-review

Synaptosomal-associated protein 25 (SNAP-25) and attention deficit hyperactivity disorder (ADHD): Evidence of linkage and association in the Irish population

Hawi, Z., Brophy, K., Kirley, A., Fitzgerald, M. & Gill, M., 8 Oct 2001, In : American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 105, 7, p. 634 1 p.

Research output: Contribution to journalArticleResearchpeer-review

2000

Nicotinic acetylcholine receptor 7 subunit gene and attention deficit hyperactivity disorder

Kent, L., Green, E., Fitzgerald, M. F., Hawi, Z., Gill, M., Thapar, A., Holmes, J., Asherson, P., Gould, A., Taylor, E., Payton, T. & Craddock, N., 7 Aug 2000, In : American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 96, 4, p. 490 1 p.

Research output: Contribution to journalArticleResearchpeer-review

50 Citations (Scopus)

No association between catechol-O-methyltransferase (COMT) gene polymorphism and attention deficit hyperactivity disorder (ADHD) in an Irish sample

Hawi, Z., Millar, N., Daly, G., Fitzgerald, M. & Gill, M., 12 Jun 2000, In : American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 96, 3, p. 282-284 3 p.

Research output: Contribution to journalArticleOtherpeer-review

No association of serotonin transporter gene polymorphisms with Attention Deficit Hyperactivity Disorder

Hawi, Z., Kirley, A., Mullins, C., Fitzgerald, M. F. & Gill, M., 7 Aug 2000, In : American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 96, 4, p. 490 1 p.

Research output: Contribution to journalArticleOtherpeer-review

86 Citations (Scopus)

No association of the dopamine DRD4 receptor (DRD4) gene polymorphism with attention deficit hyperactivity disorder (ADHD) in the Irish population

Hawi, Z., McCarron, M., Kirley, A., Daly, G., Fitzgerald, M. & Gill, M., 12 Jun 2000, In : American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 96, 3, p. 268-272 5 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

No association of the DRD2 polymorphism and attention deficit hyperactivity disorder in the Irish population

Kirley, A., Hawi, Z., Mullins, C., Fitzgerald, M. & Gill, M., 7 Aug 2000, In : American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 96, 4, p. 488 1 p.

Research output: Contribution to journalArticleOtherpeer-review

10 Citations (Scopus)

Novelty seeking traits and D4 dopamine receptors [1]

Swift, G., Larsen, B., Hawi, Z. & Gill, M., 3 Apr 2000, In : American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 96, 2, p. 222-223 2 p.

Research output: Contribution to journalLetterOtherpeer-review