Projects per year
Personal profile
Research interests
To understand pathophysiology of diabetes associated injury in kidney and blood vessels in order to identify and validate new molecular targets for development of novel therapeutic agents to prevent, retard and treat diabetic complications such as diabetic nephropathy and diabetes associated vascular disease.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research area keywords
- Diabetes
- Pathophysiology
- Diabetic Complications
- Diabetic Nephropathy
- Renal Fibrosis
- Diabetic Vascular Disease
- Cell Division Autoantigen 1 (CDA1)
- Transforming Growth Factor-beta (TGF-β)
Network
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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New strategy to safely and effectively reduce diabetic kidney disease
Chai, Z., Chalmers, D. & Cooper, M.
1/01/22 → 31/12/25
Project: Research
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Pharmacological inhibition of a novel target to reduce renal fibrosis
1/01/17 → 31/12/19
Project: Research
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Advances in clinical research in chronic kidney disease
Zou, Y., Liu, F., Cooper, M. E. & Chai, Z., 28 Sep 2021, In: Journal of Translational Internal Medicine. 9, 3, p. 146-149 4 p.Research output: Contribution to journal › Editorial › Other › peer-review
Open Access -
A Modified MTS Proliferation Assay for Suspended Cells to Avoid the Interference by Hydralazine and β-Mercaptoethanol
Wang, Y., Nguyen, D. T., Yang, G., Anesi, J., Kelly, J., Chai, Z., Ahmady, F., Charchar, F. & Golledge, J., 1 Apr 2021, In: ASSAY and Drug Development Technologies. 19, 3, p. 184-190 7 p.Research output: Contribution to journal › Article › Research › peer-review
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Association between serum uric acid and renal outcome in patients with biopsy-confirmed diabetic nephropathy
Zou, Y., Zhao, L., Zhang, J., Wang, Y., Wu, Y., Ren, H., Wang, T., Zhang, R., Wang, J., Zhao, Y., Qin, C., Xu, H., Li, L., Chai, Z., Cooper, M. E., Tong, N. & Liu, F., Oct 2021, In: Endocrine Connections. 10, 10, p. 1299-1306 8 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
Early-onset of type 2 diabetes mellitus is a risk factor for diabetic nephropathy progression: a biopsy-based study
Wu, Y., Wang, Y., Zhang, J., Zhang, R., Zhao, L., Ren, H., Zou, Y., Wang, T., Wang, J., Zhao, Y., Qin, C., Xu, H., Li, L., Chai, Z., Cooper, M. E., Tong, N. & Liu, F., 31 Mar 2021, In: Aging. 13, 6, p. 8146-8154 9 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access4 Citations (Scopus) -
Factors behind the prevalence of carbapenem-resistant Klebsiella pneumoniae in pediatric wards
Yang, Y., Liu, J., Muhammad, M., Liu, H., Min, Z., Lu, J., Zhang, L. & Chai, Z., 10 Sep 2021, In: Medicine®. 100, 36, p. e27186 8 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access
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Chinese herbal medicine for diabetic kidney disease: historical perspective, clinical evidence and new therapeutic development
Zhong-Lin Chai (Examiner)
14 Mar 2019 → 31 May 2019Activity: Examination types › Thesis Examination
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Yuxin Yang
Zhong-Lin Chai (Host)
1 Aug 2019 → 31 Dec 2020Activity: Hosting a visitor types › Hosting an academic or industry visitor
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Shu Ting Ren
Zhong-Lin Chai (Host)
1 Sep 2017 → 28 Feb 2018Activity: Hosting a visitor types › Hosting an academic or industry visitor
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Preventing kidney fibrosis by targeting MMP-9 in chronic kidney disease
Zhong-Lin Chai (Examiner)
20 Jan 2015 → 20 Mar 2015Activity: Examination types › Thesis Examination
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Baker Heart and Diabetes Institute (External organisation)
Zhong-Lin Chai (Inventor) & Mark Cooper (Inventor)
29 Jul 2010Activity: Industry, Government and Philanthropy Engagement and Partnerships › Patents › Patent