• 15 innovation walk

    Australia

Accepting PhD Students

20052023

Research output per year

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Research Output

2019

Glycan mimetics from natural products: New therapeutic opportunities for neurodegenerative disease

Wang, W., Gopal, S., Pocock, R. & Xiao, Z., 16 Dec 2019, In : Molecules. 24, 24, 23 p., 4604.

Research output: Contribution to journalReview ArticleResearchpeer-review

Open Access
File

Impaired cognitive function and altered hippocampal synaptic plasticity in mice lacking dermatan sulfotransferase Chst14/D4st1

Li, Q., Wu, X., Na, X., Ge, B., Wu, Q., Guo, X., Ntim, M., Zhang, Y., Sun, Y., Yang, J., Xiao, Z., Zhao, J. & Li, S., 11 Feb 2019, In : Frontiers in Molecular Neuroscience. 12, 10 p., 26.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Paeoniflorin attenuates impairment of spatial learning and hippocampal long-term potentiation in mice subjected to chronic unpredictable mild stress

Liu, S. C., Hu, W-Y., Zhang, W. Y., Yang, L., Li, Y., Xiao, Z-C., Zhang, M. & He, Z-Y., Sep 2019, In : Psychopharmacology. 236, 9, p. 2823-2834 12 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Post-stroke gastrodin treatment ameliorates ischemic injury and increases neurogenesis and restores the Wnt/β-Catenin signaling in focal cerebral ischemia in mice

Qiu, C. W., Liu, Z. Y., Zhang, F. L., Zhang, L., Li, F., Liu, S. Y., He, J. Y. & Xiao, Z. C., 1 Jun 2019, In : Brain Research. 1712, p. 7-15 9 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)
2018

Application of nanodiagnostics and nanotherapy to CNS diseases

Zhang, W., Wang, W., Yu, D. X., Xiao, Z. & He, Z., 1 Sep 2018, In : Nanomedicine. 13, 18, p. 2341-2371 31 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Open Access
File
8 Citations (Scopus)

APP upregulation contributes to retinal ganglion cell degeneration via JNK3

Liu, C., Zhang, C. W., Zhou, Y., Wong, W. Q., Lee, L. C., Ong, W. Y., Yoon, S. O., Hong, W., Fu, X. Y., Soong, T. W., Koo, E. H., Stanton, L. W., Lim, K. L., Xiao, Z-C. & Dawe, G. S., 1 Mar 2018, In : Cell Death and Differentiation. 25, 4, p. 661-676 16 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
6 Citations (Scopus)

Cntn6 deficiency impairs allocentric navigation in mice

Mu, D., Xu, Y., Zhao, T., Watanabe, K., Xiao, Z. C. & Ye, H., 1 Jun 2018, In : Brain and Behavior. 8, 6, 10 p., e00969.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
1 Citation (Scopus)

Wip1 knockout inhibits neurogenesis by affecting the Wnt/β-catenin signaling pathway in focal cerebral ischemia in mice

Qiu, C. W., Liu, Z. Y., Hou, K., Liu, S. Y., Hu, Y. X., Zhang, L., Zhang, F. L., Lv, K. Y., Kang, Q., Hu, W. Y., Ma, N., Jiao, Y., Bai, W. J. & Xiao, Z. C., 1 Nov 2018, In : Experimental Neurology. 309, p. 44-53 10 p.

Research output: Contribution to journalArticleResearchpeer-review

8 Citations (Scopus)
2017

Navβ2 knockdown improves cognition in APP/PS1 mice by partially inhibiting seizures and APP amyloid processing

Hu, T., Xiao, Z., Mao, R., Chen, B., Lu, M-N., Tong, J., Mei, R., Li, S-S., Xiao, Z., Zhang, L-F. & XiYang, Y-B., 16 Oct 2017, In : Oncotarget. 8, 59, p. 99284-99295 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
8 Citations (Scopus)

Proportion and difference of neural stem cells and neurons from different embryonic mouse brain tissues

Zhang, F. L., Yang, L. J. & Xiao, Z. C., 28 Jul 2017, In : Chinese Journal of Tissue Engineering Research. 21, 21, p. 3364-3369 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
2016

Amyloid precursor protein modulates Nav1.6 sodium channel currents through a Go-coupled JNK pathway

Li, S., Wang, X., Ma, Q. H., Yang, W-L., Zhang, X. G., Dawe, G. S. & Xiao, Z-C., 23 Dec 2016, In : Scientific Reports. 6, 16 p., 39320.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
3 Citations (Scopus)

Elevated neuronal excitability due to modulation of the voltage-gated sodium channel Nav1.6 by Aβ1-42

Wang, X., Zhang, X. G., Zhou, T. T., Li, N., Jang, C. Y., Xiao, Z. C., Ma, Q. H. & Li, S., 9 Mar 2016, In : Frontiers in Neuroscience. 10, 9 p., 94.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
15 Citations (Scopus)

Gamma-H2AX upregulation caused by Wip1 deficiency increases depression-related cellular senescence in hippocampus

He, Z-Y., Wang, W., Hu, W-Y., Yang, L., Li, Y., Zhang, W-Y., Yang, Y-S., Liu, S-C., Zhang, F-L., Mei, R., Xing, D., Xiao, Z-C. & Zhang, M., 30 Sep 2016, In : Scientific Reports. 6, 11 p., 34558.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
7 Citations (Scopus)

p38 MAPK inhibition improves synaptic plasticity and memory in angiotensin II-dependent hypertensive mice

Dai, H-L., Hu, W. Y., Jiang, L. H., Li, L-Y., Gaung, X. F. & Xiao, Z., 10 Jun 2016, In : Scientific Reports. 6, 10 p., 27600.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
9 Citations (Scopus)

Rosmarinic acid stimulates liver regeneration through the mTOR pathway

Lou, K., Yang, M., Duan, E., Zhao, J., Yu, C., Zhang, R., Zhang, L., Zhang, M., Xiao, Z., Hu, W. & He, Z., 1 Dec 2016, In : Phytomedicine : international journal of phytotherapy and phytopharmacology. 23, 13, p. 1574-1582 9 p.

Research output: Contribution to journalArticleResearchpeer-review

13 Citations (Scopus)

Scutellarin Alleviates Behavioral Deficits in a Mouse Model of Multiple Sclerosis, Possibly Through Protecting Neural Stem Cells

Wang, W-W., Lu, L., Bao, T-H., Zhang, H-M., Yuan, J., Miao, W., Wang, S-F. & Xiao, Z-C., 1 Feb 2016, In : Journal of Molecular Neuroscience. 58, 2, p. 210-220 11 p.

Research output: Contribution to journalArticleResearchpeer-review

22 Citations (Scopus)

Sodium Channel Voltage-Gated Beta 2 Plays a Vital Role in Brain Aging Associated with Synaptic Plasticity and Expression of COX5A and FGF-2

XiYang, Y-B., Wang, Y-C., Zhao, Y., Ru, J., Lu, B-T., Zhang, Y-N., Wang, N-C., Hu, W-Y., Liu, J., Yang, J-W., Wang, Z-J., Hao, C-G., Feng, Z-T., Xiao, Z-C., Dong, W., Quan, X-Z., Zhang, L-F. & Wang, T-H., 1 Mar 2016, In : Molecular Neurobiology. 53, 2, p. 955-967 13 p.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)

Wip1 phosphatase modulates both long-term potentiation and long-term depression through the dephosphorylation of CaMKII

He, Z-Y., Hu, W-Y., Zhang, M., Yang, Z. Z., Zhu, H-M., Xing, D., Ma, Q-H. & Xiao, Z-C., 2016, In : Cell Adhesion and Migration. 10, 3, p. 237-247 11 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)
2015

ACE2-angiotensin-(1-7)-Mas axis might be a promising therapeutic target for pulmonary arterial hypertension

Dai, H., Jiang, L., Xiao, Z-C. & Guang, X-F., 2015, In : Nature Reviews Cardiology. 12, 6, p. 374 - 374 1 p.

Research output: Contribution to journalLetterOther

10 Citations (Scopus)

Amyloid precursor protein enhances Nav1.6 sodium channel cell surface expression

Liu, C., Tan, C. K. F., Xiao, Z-C. & Dawe, G. S., 2015, In : Journal of Biological Chemistry. 290, 19, p. 12048 - 12057 10 p.

Research output: Contribution to journalArticleResearchpeer-review

14 Citations (Scopus)

APP intracellular domain acts as a transcriptional regulator of miR-663 suppressing neuronal differentiation

Shu, R., Wong, W. S. F., Ma, Q-H., Yang, Z. Z., Zhu, H., Liu, F. J., Wang, P., Ma, J., Yan, S., Polo, J. M., Bernard, C. C. A., Stanton, L. W., Dawe, G. S. & Xiao, Z., 1 Jan 2015, In : Cell Death and Disease. 6, 2, 12 p., e1651.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
17 Citations (Scopus)

Caspr4 interaction with LNX2 modulates the proliferation and neuronal differentiation of mouse neural progenitor cells

Yin, F-T., Futagawa, T., Li, D., Ma, Y-X., Lu, M-H., Lu, L., Li, S., Chen, Y., Cao, Y-J., Yang, Z. Z., Oiso, S., Nishida, K., Kuchiiwa, S., Watanabe, K., Yamada, K., Takeda, Y., Xiao, Z-C. & Ma, Q-H., 2015, In : Stem Cells and Development. 24, 5, p. 640 - 652 13 p.

Research output: Contribution to journalArticleResearchpeer-review

13 Citations (Scopus)

CXCL1 triggers caspase-3 dependent tau cleavage in long-term neuronal cultures and in the hippocampus of aged mice: Implications in Alzheimer's disease

Zhang, X-F., Zhao, Y-F., Zhu, S-W., Huang, W-J., Luo, Y., Chen, Q-Y., Ge, L-J., Li, R-S., Wang, J-F., Sun, M., Xiao, Z-C. & Fan, G-H., 2015, In : Journal of Alzheimer's Disease. 48, 1, p. 89 - 104 16 p.

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

G protein coupled receptor 50 promotes self-renewal and neuronal differentiation of embryonic neural progenitor cells through regulation of notch and wnt/beta-catenin signalings

Ma, Y-X., Wu, Z-Q., Feng, Y-J., Xiao, Z-C., Qin, X-L. & Ma, Q-H., 2015, In : Biochemical and Biophysical Research Communications. 458, 4 (Art. No: 33432), p. 836 - 842 7 p.

Research output: Contribution to journalArticleResearchpeer-review

8 Citations (Scopus)

Increased cardiovascular risk in women with kidney stones: urinary tract infection should be considered

Dai, H., Guang, X-F. & Xiao, Z-C., 2015, In : American Journal of Kidney Diseases. 65, 1, p. 169 - 175 7 p.

Research output: Contribution to journalLetterOther

2 Citations (Scopus)

Inhibition of wild-type p53-induced phosphatase 1 promotes liver regeneration in mice by direct activation of mammalian target of rapamycin

Zhang, L., Liu, L., He, Z., Li, G., Liu, J-P., Song, Z., Jin, H., Rudolph, K. L., Yang, H., Mao, Y., Zhang, L., Zhang, H., Xiao, Z. & Ju, Z., Jun 2015, In : Hepatology. 61, 6, p. 2030-2041 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
21 Citations (Scopus)

Mice deficient for wild-type p53-induced phosphatase 1 display elevated anxiety- and depression-like behaviors

Ruan, C. S., Zhou, F. H., He, Z-Y., Wang, S., Yang, C-R., Shen, Y-J., Guo, Y., Zhao, H. B., Chen, L., Liu, D., Liu, J., Baune, B. T., Xiao, Z-C. & Zhou, X-F., 2015, In : Neuroscience. 293, p. 12-22 11 p.

Research output: Contribution to journalArticleResearchpeer-review

12 Citations (Scopus)

Prolonged combination lipid therapy is associated with reduced carotid intima-media thickness

Dai, H., Guang, X-F. & Xiao, Z-C., 2015, In : Journal of Clinical Lipidology. 9, 1, p. 113 - 113 1 p.

Research output: Contribution to journalLetterOther

The Ca(2+) channel inhibitor 2-APB reverses {beta}-amyloid-induced LTP deficit in hippocampus by blocking BAX and caspase-3 hyperactivation

Hu, W-Y., He, Z-Y., Yang, L-J., Zhang, M., Xing, D. & Xiao, Z-C., 2015, In : British Journal of Pharmacology. 172, 9, p. 2273 - 2285 13 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

Wip1 deficiency impairs haematopoietic stem cell function via p53 and mTORC1 pathways

Chen, Z., Yi, W., Morita, Y., Wang, H., Cong, Y-S., Liu, J-P., Xiao, Z-C., Rudolph, K. L., Cheng, T. C. & Ju, Z., 2015, In : Nature Communications. 6, 6808, p. 1 - 11 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
27 Citations (Scopus)
2014

Amyloid precursor protein at node of Ranvier modulates nodal formation

Xu, D-E., Zhang, W-M. M., Yang, Z. Z., Zhu, H-M. M., Yan, K., Li, S., Bagnard, D., Dawe, G. S., Ma, Q-H. & Xiao, Z-C., 2014, In : Cell Adhesion and Migration. 8, 4, p. 396 - 403 8 p.

Research output: Contribution to journalArticleResearchpeer-review

12 Citations (Scopus)

Crystallization, preliminary X-ray crystallographic and cryo-electron microscopy analysis of a bifunctional enzyme fucokinase/L-fucose-1-P-guanylyltransferase from Bacteroides fragilis

Cheng, C., Gu, J., Su, J., Ding, W., Yin, J., Liang, W., Yu, X., Ma, J., Wang, P. G., Xiao, Z-C. & Liu, Z-J., 2014, In : Acta Crystallographica. Section F: Structural Biology Communications. 70, 9, p. 1206 - 1210 5 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Crystal structure of the N-terminal methyltransferase-like domain of anamorsin

Song, G., Cheng, C., Li, Y., Shaw, N., Xiao, Z-C. & Liu, Z-J., 2014, In : Proteins: Structure, Function, and Bioinformatics. 82, 6, p. 1066 - 1071 6 p.

Research output: Contribution to journalArticleResearchpeer-review

8 Citations (Scopus)

Decreased levels of serum Angiotensin-(1-7) in patients with pulmonary arterial hypertension due to congenital heart disease

Dai, H., Gong, Y., Xiao, Z-C., Guang, X-F. & Yin, X-L., 2014, In : International Journal of Cardiology. 176, 3, p. 1399 - 1401 3 p.

Research output: Contribution to journalLetterOther

9 Citations (Scopus)

Deletion of TRIM32 protects mice from anxiety- and depression-like behaviors under mild stress

Ruan, C. S., Wang, S., Shen, Y-J., Guo, Y., Yang, C-R., Zhou, F. H., Tan, L-T., Zhou, L., Liu, J., Wang, W., Xiao, Z-C. & Zhou, X-F., 2014, In : European Journal of Neuroscience. 40, 4, p. 2680 - 2690 11 p.

Research output: Contribution to journalArticleResearchpeer-review

17 Citations (Scopus)

Lamotrigine attenuates deficits in synaptic plasticity and accumulation of amyloid plaques in APP/PS1 transgenic mice

Zhang, M-Y., Zheng, C-Y., Zou, M-M., Zhu, J-W., Zhang, Y., Wang, J., Liu, C-F., Li, Q-F., Xiao, Z-C., Li, S., Ma, Q-H. & Xu, R-X., 2014, In : Neurobiology of Aging. 35, 12, p. 2713 - 2725 13 p.

Research output: Contribution to journalArticleResearchpeer-review

39 Citations (Scopus)

Making synapses strong: metaplasticity prolongs associativity of long-term memory by switching synaptic tag mechanisms

Li, Q., Rothkegel, M., Xiao, Z-C., Abraham, W. C., Korte, M. & Sajikumar, S., 2014, In : Cerebral Cortex. 24, 2, p. 353 - 363 11 p.

Research output: Contribution to journalArticleResearchpeer-review

33 Citations (Scopus)

Multiple systemic transplantations of human amniotic mesenchymal stem cells exert therapeutic effects in an ALS mouse model

Sun, H., Hou, Z., Yang, H., Meng, M., Li, P., Zou, Q., Yang, L-J., Chen, Y., Chai, H., Zhong, H., Yang, Z. Z., Zhao, J., Lai, L., Jiang, X. & Xiao, Z-C., 2014, In : Cell and Tissue Research. 357, 3, p. 571 - 582 12 p.

Research output: Contribution to journalArticleResearchpeer-review

10 Citations (Scopus)

Pulmonary arterial hypertension in HIV infection: a concise review

Dai, H., Zhang, M., Xiao, Z-C., Guang, X-F. & Yin, X-L., 2014, In : Heart Lung and Circulation. 23, 4, p. 299 - 302 4 p.

Research output: Contribution to journalArticleOther

9 Citations (Scopus)

Species-dependent neuropathology in transgenic SOD1 pigs

Yang, H., Wang, G., Sun, H., Shu, R., Liu, T., Wang, C-E., Liu, Z., Zhao, Y., Zhao, B., Ouyang, Z., Yang, D., Huang, J., Zhou, Y., Li, S., Jiang, X., Xiao, Z-C., Li, X-J. & Lai, L., 2014, In : Cell Research. 24, 4, p. 464 - 481 18 p.

Research output: Contribution to journalArticleResearchpeer-review

24 Citations (Scopus)
2013

Abnormal myelination in the spinal cord of PTPalpha-knockout mice

Ma, Q-H., Xiang, T., Yang, Z. Z., Zhang, X., Taylor, J. & Xiao, Z-C., 2013, In : Cell Adhesion and Migration. 7, 4, p. 370 - 376 7 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Bosentan and antiretroviral therapy in an HIV/HBV/HCV coinfected Chinese patient with HIV-related pulmonary arterial hypertension

Dai, H., Lu, Y., Guang, X., Xiao, Z-C., Zhang, M. & Zhang, W., 2013, In : Chinese Medical Journal. 126, 6, p. 1197 - 1198 2 p.

Research output: Contribution to journalLetterOther

5 Citations (Scopus)

Cell recognition molecule L1 promotes embryonic stem cell differentiation through the regulation of cell surface glycosylation

Li, Y., Huang, X., An, Y., Ren, F., Yang, Z. Z., Zhu, H., Zhou, L., He, X., Schachner, M., Xiao, Z-C., Ma, K. & Li, Y., 2013, In : Biochemical and Biophysical Research Communications. 440, 3, p. 405 - 412 8 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Loss of cell adhesion molecule CHL1 improves homeostatic adaptation and survival in hypoxic stress

Huang, X., Sun, J., Rong, W., Zhao, T., Li, D., Ding, X., Wu, L., Wu, K., Schachner, M., Xiao, Z-C., Zhu, L. & Fan, M., 2013, In : Cell Death and Disease. 4, 8 (Art. ID: e768), p. 1 - 9 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
3 Citations (Scopus)

Mature BDNF promotes the growth of glioma cells in vitro

Xiong, J., Zhou, L., Lim, Y., Yang, M., Zhu, Y., Li, Z., Zhou, F. H., Xiao, Z-C. & Zhou, X-F., 2013, In : Oncology Reports. 30, 6, p. 2719 - 2724 6 p.

Research output: Contribution to journalArticleResearchpeer-review

22 Citations (Scopus)

Meta-analysis supports association of a functional SNP (rs1801133) in the MTHFR gene with Parkinson's disease

Zhu, Z., Ai, Q., Wang, W. & Xiao, Z-C., 2013, In : Gene. 531, 1, p. 78 - 83 6 p.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)

ProBDNF and its receptors are upregulated in glioma and inhibit the growth of glioma cells in vitro

Xiong, J., Zhou, L., Yang, M., Lim, Y., Zhu, Y., Fu, D., Li, Z., Zhong, J-H., Xiao, Z-C. & Zhou, X., 2013, In : Neuro-Oncology. 15, 8, p. 990 - 1007 18 p.

Research output: Contribution to journalArticleResearchpeer-review

30 Citations (Scopus)

Recombinant DNA vaccine against neurite outgrowth inhibitors attenuates behavioral deficits and decreases Abeta in an Alzheimer's disease mouse model

Zhang, L., Ma, Q., Yang, W., Qi, X., Yao, Z., Liu, Y., Liang, L., Wang, X., Ma, C., Huang, L., Xu, Y., Zhu, H., Deng, W., Gao, Y., Ruan, L., Xiao, Z. & Qin, C., 2013, In : Neuropharmacology. 70, p. 200 - 210 11 p.

Research output: Contribution to journalArticleResearchpeer-review

12 Citations (Scopus)

The cell adhesion molecule L1 regulates the expression of FGF21 and enhances neurite outgrowth

Huang, X., Hu, J. H., Li, Y., Yang, Z. Z., Zhu, H., Zhou, L., Ma, K., Schachner, M., Xiao, Z-C. & Li, Y., 2013, In : Brain Research. 1530, p. 13 - 21 9 p.

Research output: Contribution to journalArticleResearchpeer-review

16 Citations (Scopus)

The changes of serum angiotensin-converting enzyme 2 in patients with pulmonary arterial hypertension due to congenital heart disease

Dai, H., Guo, Y., Guang, X., Xiao, Z-C., Zhang, M. & Yin, X-L., 2013, In : Cardiology. 124, 4, p. 208 - 212 5 p.

Research output: Contribution to journalArticleResearchpeer-review

21 Citations (Scopus)