Projects per year
Personal profile
Biography
Neurogenesis is a fundamental process of generating new neurons, which integrate into existing circuits.
Neurogenesis is important for learning and memory, ageing and neurodegenerative disorders. Both intrinsic and extrinsic mechanisms regulate neurogenesis. miRNAs are short noncoding RNAs that regulate gene expression at the posttranscriptional level that appears to be involved in multiple steps of neurogenesis. However, it is not clear how these miRNAs are modulated during neurogenesis. This proposal broadly aims to identify promoters of miRNAs, such as mir9, that mediate pathways specifically regulated neurogenesis.
http://www.med.monash.edu.au/anatomy/research/neurodegeneration-group.html
Research area keywords
- Stem Cell Biology
- Regenerative Medicine
- learning disorders
Network
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Genetic Diversity in the collaborative cross model recapitulates miRNA mediated neurogenesis
Apex Glory International Trading
22/07/19 → 31/12/23
Project: Research
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Screening and Identification of natural compounds for neural protection
1/07/20 → 30/06/21
Project: Research
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15-Day subchronic developmental toxicity studies of ursolic acid in rats
Geerlofs, L., He, Z., Xiao, S. & Xiao, Z-C., Oct 2020, In: Food and Chemical Toxicology. 144, 17 p., 111537.Research output: Contribution to journal › Article › Research › peer-review
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Absence of TRIM32 Leads to Reduced GABAergic Interneuron Generation and Autism-like Behaviors in Mice via Suppressing mTOR Signaling
Zhu, J. W., Zou, M. M., Li, Y. F., Chen, W. J., Liu, J. C., Chen, H., Fang, L. P., Zhang, Y., Wang, Z. T., Chen, J. B., Huang, W., Li, S., Jia, W. Q., Wang, Q. Q., Zhen, X. C., Liu, C. F., Li, S., Xiao, Z. C., Xu, G. Q., Schwamborn, J. C. & 3 others, , 14 May 2020, In: Cerebral Cortex. 30, 5, p. 3240-3258 19 p.Research output: Contribution to journal › Article › Research › peer-review
13 Citations (Scopus) -
COX5A plays a vital role in memory impairment associated with brain aging via the BDNF/ERK1/2 signaling pathway
Xiyang, Y-B., Liu, R., Wang, X-Y., Li, S., Zhao, Y., Lu, B-T., Xiao, Z-C., Zhang, L-F., Wang, T-H. & Zhang, J., Jul 2020, In: Frontiers in Aging Neuroscience. 12, 13 p., 215.Research output: Contribution to journal › Article › Research › peer-review
Open AccessFile -
Repeated dose (90 days) oral toxicity study of ursolic acid in Han-Wistar rats
Geerlofs, L., He, Z., Xiao, S. & Xiao, Z-C., 2020, In: Toxicology reports. 7, p. 610-623 14 p.Research output: Contribution to journal › Article › Research › peer-review
Open AccessFile8 Citations (Scopus) -
Efficacy of berberine as a preservative against mold and yeast in poultry feed
Geerlofs, L., He, Z., Xiao, S. & Xiao, Z-C., 23 Oct 2019, In: Approaches in Poultry, Dairy & Veterinary Sciences. 6, 5, p. 601-605 5 p.Research output: Contribution to journal › Article › Research
Open AccessFile