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Zhi-Cheng Xiao

Professor

 https://orcid.org/0000-0001-5172-762X

  • 15 innovation walk

    Australia

Accepting PhD Students

20052023

Research output per year

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Personal profile

Biography

Neurogenesis is a fundamental process of generating new neurons, which integrate into existing circuits.
Neurogenesis is important for learning and memory, ageing and neurodegenerative disorders. Both intrinsic and extrinsic mechanisms regulate neurogenesis. miRNAs are short noncoding RNAs that regulate gene expression at the posttranscriptional level that appears to be involved in multiple steps of neurogenesis. However, it is not clear how these miRNAs are modulated during neurogenesis. This proposal broadly aims to identify promoters of miRNAs, such as mir9, that mediate pathways specifically regulated neurogenesis.

http://www.med.monash.edu.au/anatomy/research/neurodegeneration-group.html

 

Research area keywords

  • Stem Cell Biology
  • Regenerative Medicine
  • learning disorders

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Projects

Genetic Diversity in the collaborative cross model recapitulates miRNA mediated neurogenesis

Xiao, Z.

Apex Glory International Trading

22/07/19 → 31/12/23

Project: Research

Stem cell-based reversal of immunodeficiency and Understanding the beginnings of Alzheimer's disease / Strategies to regenerate the aged or damaged immune system.

Chidgey, A. & Xiao, Z.

1/01/14 → 31/12/18

Project: Research

Research Output

Glycan mimetics from natural products: New therapeutic opportunities for neurodegenerative disease

Wang, W., Gopal, S., Pocock, R. & Xiao, Z., 16 Dec 2019, In : Molecules. 24, 24, 23 p., 4604.

Research output: Contribution to journal › Review Article › Research › peer-review

Open Access
File

Impaired cognitive function and altered hippocampal synaptic plasticity in mice lacking dermatan sulfotransferase Chst14/D4st1

Li, Q., Wu, X., Na, X., Ge, B., Wu, Q., Guo, X., Ntim, M., Zhang, Y., Sun, Y., Yang, J., Xiao, Z., Zhao, J. & Li, S., 11 Feb 2019, In : Frontiers in Molecular Neuroscience. 12, 10 p., 26.

Research output: Contribution to journal › Article › Research › peer-review

Open Access
File

Paeoniflorin attenuates impairment of spatial learning and hippocampal long-term potentiation in mice subjected to chronic unpredictable mild stress

Liu, S. C., Hu, W-Y., Zhang, W. Y., Yang, L., Li, Y., Xiao, Z-C., Zhang, M. & He, Z-Y., Sep 2019, In : Psychopharmacology. 236, 9, p. 2823-2834 12 p.

Research output: Contribution to journal › Article › Research › peer-review

2 Citations (Scopus)

Post-stroke gastrodin treatment ameliorates ischemic injury and increases neurogenesis and restores the Wnt/β-Catenin signaling in focal cerebral ischemia in mice

Qiu, C. W., Liu, Z. Y., Zhang, F. L., Zhang, L., Li, F., Liu, S. Y., He, J. Y. & Xiao, Z. C., 1 Jun 2019, In : Brain Research. 1712, p. 7-15 9 p.

Research output: Contribution to journal › Article › Research › peer-review

2 Citations (Scopus)

Application of nanodiagnostics and nanotherapy to CNS diseases

Zhang, W., Wang, W., Yu, D. X., Xiao, Z. & He, Z., 1 Sep 2018, In : Nanomedicine. 13, 18, p. 2341-2371 31 p.

Research output: Contribution to journal › Review Article › Research › peer-review

Open Access
File
7 Citations (Scopus)