• 26 Innovation Walk, Building 13F

    3800 Clayton

    Australia

Accepting PhD Students

PhD projects

https://supervisorconnect.med.monash.edu/research-projects?combine=Professor%20Zane%20Andrews

20012025

Research activity per year

Personal profile

Biography

Professor Andrews received his PhD in New Zealand at the University of Otago in 2003 and undertook postdoctoral training at Yale University, New Haven, Connecticut, USA (2004-2008). He moved to Monash University in Melbourne, Australia in 2009 and established his own laboratory.

Professor Andrews is internationally recognised for his work on the neuroendocrine control of energy homeostasis and behaviour. He is the currently Deputy Head of the Metabolism, Diabetes and Obesity Program at the Monash Biomedicine Discovery Institute, the Editor-in-Chief for Endocrinology, the president of Hypothalamic Neuroscience and Neuroendocrinology Australasia (HNNA), and a council member on the International Neuroendocrine Federation.

Professor Andrews uses animal models and viral genetic techniques to study how the brain controls food intake and associated behaviours. This includes the role of homeostatic, reward, stress and motivational systems, and how they interact to influence both the need and the desire to eat. His lab is particularly interested in why and how the brain promotes the overconsumption of highly palatable energy dense foods and how this contributes to obesity. His group uses modern neuroscience techniques such as in vivo calcium imaging, optogenetics and chemogenetics to probe the physiological and behavioural function of neural circuits responding to hunger and regulating appetite. He has primarily focused on the hormone ghrelin, as a key hormonal signal of hunger, and AgRP neurons, as key hunger-sensing, neurons. He is recognised as a world leading expert in this field and his current work focuses on how these hunger-sensing systems control food intake and related behaviours such as reward, motivation, mood, memory and cognition.

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being
  • SDG 4 - Quality Education
  • SDG 5 - Gender Equality
  • SDG 7 - Affordable and Clean Energy
  • SDG 9 - Industry, Innovation, and Infrastructure

Research area keywords

  • Satiety
  • Energy balance
  • Memory
  • Hunger
  • Hypothalamus
  • Cognition
  • Feeding behaviour
  • Dopamine
  • Ventral Tegmental Area
  • Neuroendocrinology
  • Behaviour
  • Feeding Experimental Device 3 (FED3)
  • Anti-obesity medication
  • GLP1R agonist/coagonist
  • Mood
  • In vivo Photometry
  • Motivation
  • Stress
  • GHSR
  • Growth hormone secretagogue receptor
  • transgenic mice
  • Optogenetics
  • neuropeptide y
  • Pro-opiomelanocortin
  • Arcuate nucleus
  • Diet-induced obesity
  • Calorie restriction
  • Reward
  • Semaglutide
  • Ghrelin
  • Olfaction
  • Appetite regulation
  • Calcium Imaging
  • learning
  • Reinforcement learning
  • Smell

Collaborations and top research areas from the last five years

Recent external collaboration on country/territory level. Dive into details by clicking on the dots or