Projects per year
Personal profile
Biography
Yijun is a research fellow in the Drug Delivery, Disposition and Dynamics Theme at the Monash Institute of Pharmaceutical Sciences (MIPS).
He has completed his Bachelor of Pharmacy degree with Monash University, and was awarded Pharmacy Gold Medal (2012) for his academic merits. He later completed his PhD ‘The Role of Fatty Acid-Binding Proteins (FABPs) in the Transport of Docosahexaenoic Acid and Cognition’ under the supervision of Associate Professor Joseph Nicolazzo, Professor Christopher Porter and Professor Martin Scanlon. His PhD studies pioneered the role of FABPs at the blood-brain barrier, and resulted in five original research papers and one invited review as first author. His publications have achieved the American Chemical Society Editors’ Choice Award, and Featured Article chosen by Editor. His research has been cited >250 times, which is admirable for a researcher at his stage. The outcomes of his work resulted in a brand-new research activity within MIPS that has led to the development of two Honours projects and two PhD projects, for which he is part of the supervisory team.
In 2018, Dr Pan was awarded the prestigious Japan Society for the Promotion of Science (JSPS) fellowship to undertake a two-year research program with at Tohoku University, Japan. His progression at Tohoku University is evidenced by winning the 2019 Excellent Young Researcher Award (Graduate School of Medicine, Tohoku University). His growing national and international research reputation is evidenced by invited seminar presentations to RMIT University (2017) and National University of Singapore (2019).
Yijun is currently interested in investigating the roles of FABPs in immunometabolism, and drug delivery in people with neurodegenerative diseases (e.g. Alzheimer's disease and Motor Neuron Diseases). His research is currently supported by Japan Society for the Promotion of Sciences - Grants for Promoting International Collaboration ($250K), Dementia Australia Project Grant ($75k), and FightMND Impact Grant ($250K).
- The role of FABPs in immunometabolism of astrocytes and microglia and their involvement in neurodegenerative diseases
- Precise medication use in people with Alzheimer’s disease
- Improving drug delivery in people with motor neuron disease
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
External positions
Adjunct Lecturer, Tohoku University
Research area keywords
- Alzheimer's Disease
- Lipid Metabolism
- Drug delivery
- Neuroinflammation
- Immunology
- Fatty acid-binding protein
- Microglia
- Motor Neurone Disease
- Metabolism Syndrome
Collaborations and top research areas from the last five years
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Optimising dosage regimen design in individuals with motor neuron disease
Nicolazzo, J. (Primary Chief Investigator (PCI)) & Pan, Y. (Chief Investigator (CI))
1/01/22 → 31/12/22
Project: Research
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The role of fatty acid-binding protein 3 in reducing omega-6 fatty acid induced neuroinflammation
Pan, Y. (Primary Chief Investigator (PCI))
1/11/18 → 1/12/19
Project: Research
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Personalising dosage regimens of medicines in Alzheimer's disease
Pan, Y. (Primary Chief Investigator (PCI)), Nicolazzo, J. (Chief Investigator (CI)) & Owada, Y. (Chief Investigator (CI))
Dementia Australia Research Foundation Ltd
1/05/20 → 1/01/22
Project: Research
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Clearance and transport of amyloid β by peripheral monocytes correlate with Alzheimer’s disease progression
Huang, X., Fowler, C., Li, Y., Li, Q.-X., Sun, J., Pan, Y., Jin, L., Perez, K. A., Dubois, C., Lim, Y. Y., Drysdale, C., Rumble, R. L., Chinnery, H. R., Rowe, C. C., Martins, R. N., Maruff, P., Doecke, J. D., Lin, Y., Belaidi, A. A. & Barnham, K. J. & 2 others, , Dec 2024, In: Nature Communications. 15, 1, 17 p., 7998.Research output: Contribution to journal › Article › Research › peer-review
Open Access8 Citations (Scopus) -
Iron Reduces the Trafficking of Fatty Acids from Human Immortalised Brain Microvascular Endothelial Cells Through Modulation of Fatty Acid Transport Protein 1 (FATP1/SLC27A1)
Supti, S. T., Koehn, L. M., Newman, S. A., Pan, Y. & Nicolazzo, J. A., Aug 2024, In: Pharmaceutical Research. 41, 8, p. 1631–1648 18 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
Cu(ATSM) Increases P-Glycoprotein Expression and Function at the Blood-Brain Barrier in C57BL6/J Mice
Pyun, J., Koay, H. J., Runwal, P., Mawal, C., Bush, A. I., Pan, Y., Donnelly, P. S., Short, J. L. & Nicolazzo, J. A., 3 Aug 2023, In: Pharmaceutics. 15, 8, 21 p., 2084.Research output: Contribution to journal › Article › Research › peer-review
Open Access9 Citations (Scopus) -
Fatty Acid-Binding Protein 4 is Essential for the Inflammatory and Metabolic Response of Microglia to Lipopolysaccharide
Kagawa, Y., Low, Y. L., Pyun, J., Doglione, U., Short, J. L., Pan, Y. & Nicolazzo, J. A., Sept 2023, In: Journal of Neuroimmune Pharmacology. 18, 3, p. 448-461 14 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access7 Citations (Scopus) -
Peripheral Administration of the Kv1.3-Blocking Peptide HsTX1[R14A] Improves Cognitive Performance in Senescence Accelerated SAMP8 Mice
Pan, Y., Kagawa, Y., Sun, J., Lucas, D. S. D., Takechi, R., Mamo, J. C. L., Wai, D. C. C., Norton, R. S., Jin, L. & Nicolazzo, J. A., Jul 2023, In: Neurotherapeutics. 20, 4, p. 1198-1214 17 p.Research output: Contribution to journal › Article › Research › peer-review
7 Citations (Scopus)
Prizes
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American Chemical Society Editors’ Choice Award, Molecular Pharmaceutics
Pan, Y. (Recipient), 2015
Prize: Prize (including medals and awards)
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Best Oral Presentation Award, 8th Victorian Association of Chinese PhD Students and Young Scholars Research Symposium
Pan, Y. (Recipient), 2014
Prize: Prize (including medals and awards)
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Honourable Geoffrey Connard AM Student Travelling Scholarship
Pan, Y. (Recipient), 2013
Prize: Other distinction
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Activities
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Molecular Pharmaceutics (Journal)
Pan, Y. (Peer reviewer)
27 Jan 2021Activity: Publication peer-review and editorial work types › Peer review responsibility
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Diagnosis (Journal)
Pan, Y. (Peer reviewer)
5 May 2021Activity: Publication peer-review and editorial work types › Peer review responsibility
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International Journal of Environmental Research and Public Health (Journal)
Pan, Y. (Peer reviewer)
4 Jan 2021Activity: Publication peer-review and editorial work types › Peer review responsibility
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Biomolecules (Journal)
Pan, Y. (Peer reviewer)
2 Mar 2021Activity: Publication peer-review and editorial work types › Peer review responsibility
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Molecular Oncology (Journal)
Pan, Y. (Peer reviewer)
7 Apr 2021Activity: Publication peer-review and editorial work types › Peer review responsibility
Press/Media
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Survey - Precise medication use in people with dementia
1/09/20
1 Media contribution
Press/Media: Public Engagement Activities
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Study reveals Alzheimer's patients may need dosing changes in medicines prescribed for other conditions
16/04/20
1 Media contribution
Press/Media: Blogs, Podcasts and Social Media › Social Media Article
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Alzheimer's patients may need dosing changes in medicines prescribed for other conditions
15/04/20
1 Media contribution
Press/Media: Blogs, Podcasts and Social Media › Social Media Article
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Article recommended by Alzforum
8/04/20
1 Media contribution
Press/Media: Blogs, Podcasts and Social Media › Social Media Mentions