• 19 Innovation Walk, Monash BDI

20052018
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Personal profile

Biography

Currently, Yi Tian is working with Professor Jamie Rossjohn and Dr. Hugh Reid, at Monash University, Melbourne, Australia, in collaboration with scientists at Janssen Research and Development, exploring the molecular basis behind the development of rheumatoid arthritis, with special focus on major histocompatibility complex (MHC) Class II antigen presenting molecules.

Yi Tian completed her Ph.D. studies under the supervision of Associate Professor Alexander McLellan and Professor Robert Walker, at the University of Otago, New Zealand, where she investigated the role of soluble MHC class II in kidney transplant rejection. Her first postdoctoral position was in Professor Edward Baker's laboratory at the University of Auckland, New Zealand, where she focused on protein crystallography. She has a keen interest in understanding how our immune system protects against microbial infection and also in how undesirable immune responses can lead to life- threatening conditions such as autoimmune disease and transplant rejection.

Keywords

  • Structural Biology
  • Autoimmunity
  • immunology and inflammation
  • Molecular Biology

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Research Output 2005 2018

The interplay between citrullination and HLA-DRB1 polymorphism in shaping peptide binding hierarchies in rheumatoid arthritis

Ting, Y. T., Petersen, J., Ramarathinam, S. H., Scally, S. W., Loh, K. L., Thomas, R., Suri, A., Baker, D. G., Purcell, A. W., Reid, H. H. & Rossjohn, J., 2 Mar 2018, In : Journal of Biological Chemistry. 293, 9, p. 3236-3251 16 p.

Research output: Contribution to journalArticleResearchpeer-review

Molecular basis for increased susceptibility of Indigenous North Americans to seropositive rheumatoid arthritis

Scally, S. W., Law, S. C., Ting, Y. T., Heemst, J. V., Sokolove, J., Deutsch, A. J., Bridie Clemens, E., Moustakas, A. K., Papadopoulos, G. K., Woude, D. V. D., Smolik, I., Hitchon, C. A., Robinson, D. B., Ferucci, E. D., Bernstein, C. N., Meng, X., Anaparti, V., Huizinga, T., Kedzierska, K., Reid, H. H. & 5 othersRaychaudhuri, S., Toes, R. E., Rossjohn, J., El-Gabalawy, H. & Thomas, R., 1 Nov 2017, In : Annals of the Rheumatic Diseases. 76, 11, p. 1915-1923 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Staphylococcal enterotoxin-like X (SElX) is a unique superantigen with functional features of two major families of staphylococcal virulence factors

Langley, R. J., Ting, Y. T., Clow, F., Young, P. G., Radcliff, F. J., Choi, J. M., Sequeira, R. P., Holtfreter, S., Baker, H. & Fraser, J. D., 1 Sep 2017, In : PLoS Pathogens. 13, 9, 29 p., e1006549.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Peptide binding to a bacterial signal peptidase visualized by peptide tethering and carrier-driven crystallization

Ting, Y. T., Harris, P. W. R., Batot, G., Brimble, M. A., Baker, E. N. & Young, P. G., 2016, In : IUCrJ. 3, p. 10-19 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Activities 2008 2017

  • 4 Contribution to conference
  • 1 Grant review responsibilities
  • 1 Public event

PharmAus2017

Yi Tian Ting (Contributor)
5 Sep 2017

Activity: Community Talks, Presentations, Exhibitions and EventsPublic event

American Crystallographic Association 2015

Yi Tian Ting (Session chair)
25 Jul 201529 Jul 2015

Activity: Participating in or organising an event typesContribution to conference

American Crystallography Association 2014

Yi Tian Ting (Speaker)
24 May 201428 May 2014

Activity: Participating in or organising an event typesContribution to conference

External Grant Reviewer for Kidney Research UK (Invited)

Yi Tian Ting (Fellow)
2014

Activity: External Academic EngagementGrant review responsibilities

Immunity for Life - Immunology for Health

Yi Tian Ting (Speaker)
13 Sep 200916 Sep 2009

Activity: Participating in or organising an event typesContribution to conference

Press / Media

JBC Author Profile

Yi Tian Ting

5/02/18

1 media contribution

Press/Media: Profile/Interview

Rheumatoid arthritis study rated among top by journal

Yi Tian Ting

9/01/18

1 item of media coverage

Press/Media: Profile/Interview

Nature Reviews: Microbiology - In a class of their own

Yi Tian Ting

1/11/07

1 item of media coverage

Press/Media: Article/Feature