20082019

Research output per year

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Article

Early sedation with dexmedetomidine in critically ill patients

Shehabi, Y., Howe, B. D., Bellomo, R., Arabi, Y. M., Bailey, M., Bass, F. E., Bin Kadiman, S., McArthur, C. J., Murray, L., Reade, M. C., Seppelt, I. M., Takala, J., Wise, M. P. & Webb, S. A., 27 Jun 2019, In : New England Journal of Medicine. 380, 26, p. 2506-2517 12 p.

Research output: Contribution to journalArticleResearchpeer-review

24 Citations (Scopus)

Erythropoietin in traumatic brain injury associated acute kidney injury: A randomized controlled trial

Skrifvars, M. B., Moore, E., Mårtensson, J., Bailey, M., French, C., Presneill, J., Nichol, A., Little, L., Duranteau, J., Huet, O., Haddad, S., Arabi, Y., McArthur, C., Cooper, D. J., Bellomo, R. & The EPO-TBI Investigators and the ANZICS Clinical Trials Group, Feb 2019, In : Acta Anaesthesiologica Scandinavica. 63, 2, p. 200-207 8 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Maximal Recruitment Open Lung Ventilation in Acute Respiratory Distress Syndrome (PHARLAP): A Phase II, Multicenter Randomized Controlled Clinical Trial

Hodgson, C. L., Cooper, D. J., Arabi, Y., King, V., Bersten, A., Bihari, S., Brickell, K., Davies, A., Fahey, C., Fraser, J., McGuinness, S., Murray, L., Parke, R., Paul, E., Tuxen, D., Vallance, S., Young, M. & Nichol, A., Dec 2019, In : American Journal of Respiratory and Critical Care Medicine. 200, 11, p. 1363-1372 10 p.

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)
2018

Cause and Timing of Death and Subgroup Differential Effects of Erythropoietin in the EPO-TBI Study

Skrifvars, M. B., French, C., Bailey, M., Presneill, J., Nichol, A., Little, L., Durantea, J., Huet, O., Haddad, S., Arabi, Y., McArthur, C., Cooper, D. J., Bellomo, R. & EPO-TBI Investigators and the ANZICS Clinical Trials Group, 15 Jan 2018, In : Journal of Neurotrauma. 35, 2, p. 333-340 8 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Effect of piperacillin-tazobactam vs meropenem on 30-day mortality for patients with e coli or Klebsiella pneumoniae bloodstream infection and ceftriaxone resistance

Harris, P. N. A., Tambyah, P. A., Lye, D. C., Mo, Y., Lee, T. H., Yilmaz, M., Alenazi, T. H., Arabi, Y., Falcone, M., Bassetti, M., Righi, E., Rogers, B. A., Kanj, S., Bhally, H., Iredell, J., Mendelson, M., Boyles, T. H., Looke, D., Miyakis, S., Walls, G. & 15 others, Al Khamis, M., Zikri, A., Crowe, A., Ingram, P., Daneman, N., Griffin, P., Athan, E., Lorenc, P., Baker, P., Roberts, L., Beatson, S. A., Peleg, A. Y., Harris-Brown, T., Paterson, D. L. & for the MERINO Trial Investigators and the Australasian Society for Infectious Disease Clinical Research Network (ASID-CRN), 11 Sep 2018, In : JAMA - Journal of the American Medical Association. 320, 10, p. 984-994 11 p.

Research output: Contribution to journalArticleResearchpeer-review

114 Citations (Scopus)

Permissive hypercapnia, alveolar recruitment and low airway pressure (PHARLAP): A protocol for a phase 2 trial in patients with acute respiratory distress syndrome

Hodgson, C., Cooper, D. J., Arabi, Y., Bennett, V., Bersten, A., Brickell, K., Davies, A., Fahey, C., Fraser, J., McGuinness, S., Murray, L., Parke, R., Tuxen, D., Vallance, S., Young, M., Nichol, A. D. & on behalf of the PHARLAP Study Investigators and the Australian and New Zealand Intensive Care Society Clinical Trials Group, 1 Jun 2018, In : Critical Care and Resuscitation. 20, 2, p. 139-149 11 p.

Research output: Contribution to journalArticleOtherpeer-review

3 Citations (Scopus)
2017

Erythropoietin in patients with traumatic brain injury and extracranial injury – A post hoc analysis of the EPO-TBI trial

Skrifvars, M. B. B., Bailey, M., French, C., Presneill, J., Nichol, A., Little, L., Duranteau, J., Huet, O., Haddad, S., Arabi, Y., McArthur, C., Cooper, D. J., Bellomo, R. & For the EPO-TBI investigators and the ANZICS Clinical Trials Group, Sep 2017, In : The Journal of Trauma and Acute Care Surgery. 83, 3, p. 449-456 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
8 Citations (Scopus)

Geo-economic variations in epidemiology, patterns of care, and outcomes in patients with acute respiratory distress syndrome: insights from the LUNG SAFE prospective cohort study

Laffey, J. G., Madotto, F., Bellani, G., Pham, T., Fan, E., Brochard, L., Amin, P., Arabi, Y., Bajwa, E. K., Bruhn, A., Cerny, V., Clarkson, K., Heunks, L., Kurahashi, K., Laake, J. H., Lorente, J. A., McNamee, L., Nin, N., Palo, J. E., Piquilloud, L. & 11 others, Qiu, H., Jiménez, J. I. S., Esteban, A., McAuley, D. F., van Haren, F., Ranieri, M., Rubenfeld, G., Wrigge, H., Slutsky, A. S., Pesenti, A. & on behalf of the LUNG SAFE Investigators and the ESICM Trials Group, 1 Aug 2017, In : The Lancet Respiratory Medicine. 5, 8, p. 627-638 12 p.

Research output: Contribution to journalArticleResearchpeer-review

33 Citations (Scopus)

Noninvasive Ventilation of Patients with Acute Respiratory Distress Syndrome: Insights from the LUNG SAFE Study

Bellani, G., Laffey, J. G., Pham, T., Madotto, F., Fan, E., Brochard, L., Esteban, A., Gattinoni, L., Bumbasirevic, V., Piquilloud, L., Van Haren, F., Larsson, A., McAuley, D. F., Bauer, P. R., Arabi, Y. M., Ranieri, M., Antonelli, M., Rubenfeld, G. D., Taylor Thompson, B., Wrigge, H. & 3 others, Slutsky, A. S., Pesenti, A. & on behalf of the LUNG SAFE Investigators and the ESICM Trials Group, 1 Jan 2017, In : American Journal of Respiratory and Critical Care Medicine. 195, 1, p. 67-77 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
96 Citations (Scopus)

Quantifying the Effects of Prior Acetyl-Salicylic Acid on Sepsis-Related Deaths: An Individual Patient Data Meta-Analysis Using Propensity Matching

Trauer, J., Muhi, S., McBryde, E. S., Al Harbi, S. A., Arabi, Y. M., Boyle, A. J., Cartin-Ceba, R., Chen, W., Chen, Y-T., Falcone, M., Gajic, O., Godsell, J., Gong, M. N., Kor, D., Lösche, W., McAuley, D. F., O'Neal, H. R., Osthoff, M., Otto, G. P., Sossdorf, M. & 9 others, Tsai, M. J., Valerio-Rojas, J. C., van der Poll, T., Violi, F., Ware, L., Widmer, A. F., Wiewel, M. A., Winning, J. & Eisen, D. P., 1 Nov 2017, In : Critical Care Medicine. 45, 11, p. 1871-1879 9 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

Severe hypercapnia and outcome of mechanically ventilated patients with moderate or severe acute respiratory distress syndrome

Nin, N., Muriel, A., Peñuelas, O., Brochard, L., Lorente, J. A., Ferguson, N. D., Raymondos, K., Ríos, F., Violi, D. A., Thille, A. W., González, M., Villagomez, A. J., Hurtado, J., Davies, A. R., Du, B., Maggiore, S. M., Soto, L., D’Empaire, G., Matamis, D., Abroug, F. & 14 others, Moreno, R. P., Soares, M. A., Arabi, Y., Sandi, F., Jibaja, M., Amin, P., Koh, Y., Kuiper, M. A., Bülow, H. H., Zeggwagh, A. A., Anzueto, A., Sznajder, J. I., Esteban, A. & for the VENTILA Group, 1 Feb 2017, In : Intensive Care Medicine. 43, 2, p. 200-208 9 p.

Research output: Contribution to journalArticleResearchpeer-review

58 Citations (Scopus)

The impact of a multifaceted intervention including sepsis electronic alert system and sepsis response team on the outcomes of patients with sepsis and septic shock

Arabi, Y. M., Al-Dorzi, H. M., Alamry, A., Hijazi, R., Alsolamy, S., Al Salamah, M., Tamim, H. M., Al-Qahtani, S., Al-Dawood, A., Marini, A. M., Al Ehnidi, F. H., Mundekkadan, S., Matroud, A., Mohamed, M. S. & Taher, S., Dec 2017, In : Annals of Intensive Care. 7, 10 p., 57.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
7 Citations (Scopus)

The SPICE III study protocol and analysis plan: a randomised trial of early goal-directed sedation compared with standard care in mechanically ventilated patients (Protocol)

Shehabi, Y., Forbes, A. B., Arabi, Y., Bass, F., Bellomo, R., Kadiman, S., Howe, B. D., McArthur, C., Reade, M. C., Seppelt, I., Takala, J., Webb, S., Wise, M. P. & for the SPICE III study investigators, the Australian and New Zealand Intensive Care Society Clinical Trials Group and the Australian and New Zealand Intensive Care Research Centre, 1 Dec 2017, In : Critical Care and Resuscitation. 19, 4, p. 318-326 9 p.

Research output: Contribution to journalArticleOtherpeer-review

4 Citations (Scopus)

Venous thromboembolic events in critically ill traumatic brain injury patients

Skrifvars, M. B., Bailey, M., Presneill, J., French, C., Nichol, A., Little, L., Duranteau, J., Huet, O., Haddad, S., Arabi, Y., McArthur, C., Cooper, D. J., Bellomo, R. & For The Epo-Tbi Investigators, T. E-T. I., Mar 2017, In : Intensive Care Medicine. 43, 3, p. 419-428 10 p.

Research output: Contribution to journalArticleResearchpeer-review

25 Citations (Scopus)

Withholding Pantoprazole for Stress Ulcer Prophylaxis in Critically Ill Patients: A Pilot Randomized Clinical Trial and Meta-Analysis∗

Alhazzani, W., Guyatt, G., Alshahrani, M., Deane, A. M., Marshall, J. C., Hall, R., Muscedere, J., English, S. W., Lauzier, F., Thabane, L., Arabi, Y. M., Karachi, T., Rochwerg, B., Finfer, S., Daneman, N., Alshamsi, F., Zytaruk, N., Heel-Ansdell, D. & Cook, D., Jul 2017, In : Critical Care Medicine. 45, 7, p. 1121-1129 9 p.

Research output: Contribution to journalArticleResearchpeer-review

36 Citations (Scopus)
2015

Competing risk analysis for evaluation of dalteparin versus unfractionated heparin for venous thromboembolism in medical-surgical critically ill patients

Li, G., Cook, D. J., Levine, M. A. H., Guyatt, G., Crowther, M., Heels-Ansdell, D., Holbrook, A., Lamontagne, F., Walter, S. D., Ferguson, N., Finfer, S. R., Arabi, Y. M., Bellomo, R., Cooper, D. J. & Thabane, L., 2015, In : Medicine. 94, 36, p. 1 - 8 8 p., e1479.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
8 Citations (Scopus)

Computerized physician order entry of a sedation protocol is not associated with improved sedation practice or outcomes in critically ill patients

Haddad, S., Gonzales, C. B., Deeb, A. M., Tamim, H. M., AlDawood, A. S., Al Babtain, I., Naidu, B. S. & Arabi, Y. M., 2015, In : BMC Anesthesiology. 15, Article No. 177, p. 1 - 10 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
2 Citations (Scopus)
2014

Cost-effectiveness of dalteparin vs unfractionated heparin for the prevention of venous thromboembolism in critically ill patients

Fowler, R., Mittmann, N., Geerts, W., Heels-Ansdell, D., Gould, M., Guyatt, G., Krahn, M., Finfer, S. R., Pinto, R., Chan, B., Ormanidhi, O., Arabi, Y. M., Qushmaq, I., Rocha, M. G., Dodek, P., Mcintyre, L., Hall, R. I., Ferguson, N., Mehta, S., Marshall, J. C. & 12 others, Doig, C. J., Muscedere, J., Jacka, M. J., Klinger, J. R., Vlahakis, N. E., Orford, N., Seppelt, I. M., Skrobik, Y., Sud, S., Cade, J. F., Cooper, D. J. & Cook, D. J., 2014, In : JAMA. 312, 20, p. 2135 - 2145 11 p.

Research output: Contribution to journalArticleResearchpeer-review

31 Citations (Scopus)

Economic evaluation of the prophylaxis for thromboembolism in critical care trial (E-PROTECT): Study protocol for a randomized controlled trial

Fowler, R. A., Mittmann, N., Geerts, W. H., Heels-Ansdell, D., Gould, M. K., Guyatt, G., Krahn, M., Finfer, S., Pinto, R., Chan, B., Ormanidhi, O., Arabi, Y., Qushmaq, I., Rocha, M. G., Dodek, P., Mcintyre, L., Hall, R., Ferguson, N. D., Mehta, S., Marshall, J. C. & 14 others, Doig, C. J., Muscedere, J., Jacka, M. J., Klinger, J. R., Vlahakis, N. E., Orford, N., Seppelt, I., Skrobik, Y. K., Sud, S., Cade, J. F., Cooper, J., Cook, D. J., Canadian Critical Care Trials Group & Australia and New Zealand Intensive Care Society Clinical Trials Group, 20 Dec 2014, In : Trials. 15, 1, 11 p., 502.

Research output: Contribution to journalArticleOtherpeer-review

Open Access
5 Citations (Scopus)
2013

Co-enrollment of critically ill patients into multiple studies: patterns, predictors and consequences

Cook, D., McDonald, E., Smith, O., Zytaruk, N., Heels-Ansdell, D., Watpool, I., McArdle, T., Matte, A., Clarke, F., Vallance, S., Finfer, S., Galt, P., Crozier, T. M. E., Fowler, R., Arabi, Y., Woolfe, C., Orford, N., Hall, R., Adhikari, N. KJ., Ferland, M-C. & 2 others, Marshall, J. & Meade, M., 2013, In : Critical Care. 17, 1 (Art. No.: R1), p. 1 - 11 11 p.

Research output: Contribution to journalArticleOther

13 Citations (Scopus)

Evolution of mortality over time in patients receiving mechanical ventilation

Esteban, A., Frutos-Vivar, F., Muriel, A., Ferguson, N., Penuelas, O., Abraira, V., Raymondos, K., Rios, F., Nin, N., Apezteguia, C., Violi, D. A., Thille, A. W., Brochard, L., Gonzalez, M., Villagomez, A., Hurtado, J., Davies, A. R., Du, B., Maggiore, S., Pelosi, P. & 16 others, Soto, L., Tomicic, V., D'Empaire, G., Matamis, D., Abroug, F., Moreno, R., Soares, M. A., Arabi, Y., Sandi, F., Jibaja, M., Amin, P., Koh, Y., Kuiper, M., Bulow, H-H., Zeggwagh, A. A. & Anzueto, A., 2013, In : American Journal of Respiratory and Critical Care Medicine. 188, 2, p. 220 - 230 11 p.

Research output: Contribution to journalArticleResearchpeer-review

274 Citations (Scopus)
2011

Decompressive craniectomy in diffuse traumatic brain injury

Cooper, D., Rosenfeld, J., Murray, L., Arabi, Y., Davies, A., D'Urso, P., Kossmann, T. K., Ponsford, J., Seppelt, I. M., Reilly, P. & Wolfe, R., 2011, In : New England Journal of Medicine. 364, 16, p. 1493 - 1502 10 p.

Research output: Contribution to journalArticleResearchpeer-review

816 Citations (Scopus)
2008

Ventilation strategy using low tidal volumes, recruitment maneuvers, and high positive end-expiratory pressure for acute lung injury and acute respiratory distress syndrome: A randomized controlled trial

Meade, M. O., Cook, D. J., Guyatt, G., Slutsky, A. S., Arabi, Y. M., Cooper, D. J., Davies, A. R., Hand, L. E., Zhou, Q., Thabane, L., Austin, P., Lapinsky, S., Baxter, A., Russell, J., Skrobik, Y., Ronco, J. J. & Stewart, T. E., 2008, In : JAMA. 299, 6, p. 637 - 645 9 p.

Research output: Contribution to journalArticleResearchpeer-review

867 Citations (Scopus)